In Vitro and Cell Imaging-Based Analysis of Protease Activity Using Nanoparticles
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 김계백 | - |
dc.contributor.author | 김영필 | - |
dc.date.accessioned | 2022-07-07T02:39:32Z | - |
dc.date.available | 2022-07-07T02:39:32Z | - |
dc.date.created | 2021-05-14 | - |
dc.date.issued | 2018-09 | - |
dc.identifier.issn | 1226-976X | - |
dc.identifier.uri | https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/142617 | - |
dc.description.abstract | Proteases are one of the most abundant classes of enzymes in living organisms and have been considered major targets for drug development. However, despite the ability to specifically cleave their substrates, many attempts to assay protease activity have generally relied upon the use of gel zymography or fluorophore-labeled peptide substrates, which is limited in rapid and multiplex analysis. Here we review the recent advances in nanoparticle (NP)-utilized assays of protease activity focused on in vitro and cell imaging-based approaches. Owing to large surface area and unprecedented physical properties of NPs, these approaches are anticipated to facilitate many applications related to protease activity-based disease diagnosis and drug discovery. | - |
dc.language | 한국어 | - |
dc.language.iso | ko | - |
dc.publisher | 한국세라믹학회 | - |
dc.title | In Vitro and Cell Imaging-Based Analysis of Protease Activity Using Nanoparticles | - |
dc.title.alternative | 나노입자를 활용한 In vitro 및 세포이미징 기반 단백질분해 효소활성 분석법 | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | 김영필 | - |
dc.identifier.doi | 10.31613/ceramist.2018.21.3.05 | - |
dc.identifier.bibliographicCitation | 세라미스트, v.21, no.3, pp.204 - 215 | - |
dc.relation.isPartOf | 세라미스트 | - |
dc.citation.title | 세라미스트 | - |
dc.citation.volume | 21 | - |
dc.citation.number | 3 | - |
dc.citation.startPage | 204 | - |
dc.citation.endPage | 215 | - |
dc.type.rims | ART | - |
dc.type.docType | 정기 학술지(Review) | - |
dc.description.journalClass | 2 | - |
dc.description.isOpenAccess | N | - |
dc.description.journalRegisteredClass | other | - |
dc.subject.keywordAuthor | nanoparticle | - |
dc.subject.keywordAuthor | protease | - |
dc.subject.keywordAuthor | enzyme activity | - |
dc.subject.keywordAuthor | cell imaging | - |
dc.identifier.url | https://scholar.kyobobook.co.kr/article/detail/4010028154104 | - |
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