SYNTHESIS OF N-HETEROPOLYCYCLIC COMPOUNDS INCLUDING QUINAZOLINONE SKELETON USING FRIEDEL-CRAFTS ALKYLATION
- Authors
- Oh, Bu Keun; Ko, Eun Bi; Han, Jin Wook; Oh, Chang Ho
- Issue Date
- Jan-2015
- Publisher
- TAYLOR & FRANCIS INC
- Keywords
- Friedel-Crafts alkylation; Knoevenagel condensation; N-heteropolycycle; quinazolinone
- Citation
- SYNTHETIC COMMUNICATIONS, v.45, no.6, pp.768 - 776
- Indexed
- SCIE
SCOPUS
- Journal Title
- SYNTHETIC COMMUNICATIONS
- Volume
- 45
- Number
- 6
- Start Page
- 768
- End Page
- 776
- URI
- https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/143266
- DOI
- 10.1080/00397911.2014.987353
- ISSN
- 0039-7911
- Abstract
- A simple method to synthesize N-heteropolycyclic quinazolinones was developed including Knoevenagel condensation of quinazolines and aldehydes and Friedel-Craft alkylation as key steps. Knoevenagel reaction of 2-methyl-3-phenylquinazolin-4(3H)-one proceeded smoothly under a basic condition and subsequent Friedel-Craft alkylation with BrOnsted acid gave the N-heteropolycyclic quinazolinones in good yields. Furthermore, these new polycyclic compounds were converted into organic molecules having a long -conjugation system by treatment of 2,3-dichloro-5,6-dicyanobenzoquinone (DDQ) to utilize them as organic dyes.
- Files in This Item
-
Go to Link
- Appears in
Collections - 서울 자연과학대학 > 서울 화학과 > 1. Journal Articles
![qrcode](https://api.qrserver.com/v1/create-qr-code/?size=55x55&data=https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/143266)
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.