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NHC-catalyzed oxidative cyclization reaction for the synthesis of 3-substituted phthalides
- Authors
- Youn, So Won; Song, Hyoung Sub; Park, Jong Hyub
- Issue Date
- Apr-2014
- Publisher
- ROYAL SOC CHEMISTRY
- Citation
- ORGANIC & BIOMOLECULAR CHEMISTRY, v.12, no.15, pp.2388 - 2393
- Indexed
- SCIE
SCOPUS
- Journal Title
- ORGANIC & BIOMOLECULAR CHEMISTRY
- Volume
- 12
- Number
- 15
- Start Page
- 2388
- End Page
- 2393
- ISSN
- 1477-0520
- Abstract
- An efficient NHC-catalyzed domino oxidation/oxa-Michael addition reaction of 2-alkenylbenzaldehydes has been developed to afford 3-substituted phthalides bearing a C3-stereogenic center with a broad substrate scope and wide functional group tolerance. The preliminary results of the asymmetric process have been provided as well.
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Related Researcher
- Youn, So Won
- COLLEGE OF NATURAL SCIENCES (DEPARTMENT OF CHEMISTRY)