A Case of Livedoid Vasculopathy Successfully Treated with Sulodexideopen access
- Authors
- Song, Chang Hwa; Shin, Dong Seok; Jang, Ju Wang; Kim, Tae Lim; Kim, Young Gyun; Kim, Joung Soo; Seo, Hyun-Min
- Issue Date
- Dec-2020
- Publisher
- KOREAN DERMATOLOGICAL ASSOC
- Keywords
- Anticoagulants; Heparinoids; Livedoid; Sulodexide; Vasculopathy
- Citation
- ANNALS OF DERMATOLOGY, v.32, no.6, pp.508 - 511
- Indexed
- SCIE
SCOPUS
KCI
- Journal Title
- ANNALS OF DERMATOLOGY
- Volume
- 32
- Number
- 6
- Start Page
- 508
- End Page
- 511
- URI
- https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/144217
- DOI
- 10.5021/ad.2020.32.6.508
- ISSN
- 1013-9087
- Abstract
- We report a 29-year-old female with a one-month history of non-healing multiple erythematous to violaceous plaques with crusts over both legs and feet. Tender, scarring ulcers with surrounding erythema were present. The clinical manifestation, together with histopathologic findings of fibrinoid plugs within vascular lumens and walls, as well as red blood cell extravasation, led to diagnosis of livedoid vasculopathy. The patient experienced recurrent painful violaceous plaques with ulcerations during the two years of treatment with oral pentoxifylline 400 mg three times daily. The cutaneous lesions and symptoms dramatically improved after the treatment regimen changed to oral sulodexide (250 lipasemic units) three times daily. Sulodexide, a highly purified mixture of glycosaminoglycans including dermatan sulfate and low-molecular weight heparin, could be an effective therapy for recalcitrant livedoid vasculopathy. Herein, we report a case of livedoid vasculopathy treated with sulodexide, which has not previously been reported.
- Files in This Item
-
- Appears in
Collections - 서울 의과대학 > 서울 피부과학교실 > 1. Journal Articles
![qrcode](https://api.qrserver.com/v1/create-qr-code/?size=55x55&data=https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/144217)
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.