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Phylogenetic Analysis for the Origin of Typhoid Fever Outbreak on Jeju Island, Korea, in 2017open access

Authors
Lee, Keun HwaYoo, Jeong RaeKim, Young ReeHeo, Sang Taek
Issue Date
Sep-2020
Publisher
KOREAN SOC ANTIMICROBIAL THERAPY
Keywords
Phylogenetic analysis; Outbreak; Typhoid fever; Jeju Island; Korea
Citation
INFECTION AND CHEMOTHERAPY, v.52, no.3, pp.421 - 426
Indexed
SCOPUS
KCI
Journal Title
INFECTION AND CHEMOTHERAPY
Volume
52
Number
3
Start Page
421
End Page
426
URI
https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/145219
DOI
10.3947/ic.2020.52.3.421
ISSN
2093-2340
Abstract
In June 2017, on Jeju Island, six patients were diagnosed with typhoid fever. All six patients were admitted to our hospital with fever, all of them had been working at the same hotel. The gyrA and gyrB genes of four out of six Salmonella typhi cases were amplified by polymerase chain reaction. The phylogenetic tree of the genes showed that the S. Typhi isolates from Jeju Island in 2017 had the same genotype and were similar to isolates from the United Kingdom. The origin of the isolates of the outbreak was the same, and the disease strain may have been imported from outside of Korea.
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