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Generation of human induced pluripotent stem cell line from Alzheimer's disease patient with PSEN2 N141I mutation using integration-free non-viral methodopen access
- Issue Date
- Aug-2020
- Publisher
- ELSEVIER
- Citation
- STEM CELL RESEARCH, v.47, pp.1 - 5
- Indexed
- SCIE
SCOPUS
- Journal Title
- STEM CELL RESEARCH
- Volume
- 47
- Start Page
- 1
- End Page
- 5
- ISSN
- 1873-5061
- Abstract
- Induced pluripotent stem cell (iPSC) line HUi001-A was reprogrammed from skin fibroblasts via non-integrating, virus free self-replicating RNA. Skin fibroblasts from an 81-year-old female Caucasian familial Alzheimer's disease patient of Volga German family carrying N141I mutation in the PSEN2 gene (familial AD4, clinical summary confirmed Alzheimer's disease) was obtained from the Coriell Institute (AG09908). Generated iPSCs were characterized and pluripotency was confirmed.
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Collections - 서울 의과대학 > 서울 생화학·분자생물학교실 > 1. Journal Articles
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Related Researcher
- Lee, Sang Hun
- COLLEGE OF MEDICINE (DEPARTMENT OF BIOCHEMISTRY & MOLECULAR BIOLOGY)