Efficient, Simple Production of Corresponding Alcohols from Supplemented C₂-C₈Carboxylic Acids inEscherichia coliUsing Acyl-CoA Transferase fromMegasphaera hexanoica
DC Field | Value | Language |
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dc.contributor.author | Park, Hyojung | - |
dc.contributor.author | Jeon, Byoung Seung | - |
dc.contributor.author | Sang, Byoung-In | - |
dc.date.accessioned | 2022-07-07T19:57:23Z | - |
dc.date.available | 2022-07-07T19:57:23Z | - |
dc.date.created | 2021-05-11 | - |
dc.date.issued | 2020-08 | - |
dc.identifier.issn | 1226-8372 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/145362 | - |
dc.description.abstract | The accumulation of short-chain carboxylic acids (SCCAs), such as acetic acid (C-2), propionic acid (C-3), butyric acid (C-4), and valeric acid (C-5), produced by acetogens in the anaerobic digestion (AD) process hampers the maintenance of stable AD processes in biomethane production. The conversion of various SCCAs to the corresponding alcohols can be a good solution not only for utilizing abandoned or harmful SCCAs and producing useful alcohols but also for increasing the efficiency of the biogas production process. ACT01_02765 (acyl-CoA transferase) fromMegasphaera hexanoicaquickly and easily converted C-2-C(8)carboxylic acids into the corresponding alcohols inEscherichia coliwith AdhE2 (alcohol dehydrogenase) fromClostridium acetobutylicum. E. coli(ACT01_02765 and AdhE2) converted carboxylic acids to the corresponding alcohols with a conversion yield that was approximately 40 times higher and a conversion rate that was approximately 10-50 times faster than those ofE. coli(Ptb-Buk and AdhE2). The enzymatic machinery inE. coli(ACT01_02765 and AdhE2) is effective for carboxylic acids of different carbon chain lengths, resulting in the production of propanol, butanol, pentanol, hexanol, heptanol, and octanol. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | KOREAN SOC BIOTECHNOLOGY & BIOENGINEERING | - |
dc.title | Efficient, Simple Production of Corresponding Alcohols from Supplemented C₂-C₈Carboxylic Acids inEscherichia coliUsing Acyl-CoA Transferase fromMegasphaera hexanoica | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Sang, Byoung-In | - |
dc.identifier.doi | 10.1007/s12257-020-0163-x | - |
dc.identifier.scopusid | 2-s2.0-85089564219 | - |
dc.identifier.wosid | 000561715600002 | - |
dc.identifier.bibliographicCitation | BIOTECHNOLOGY AND BIOPROCESS ENGINEERING, v.25, no.4, pp.599 - 606 | - |
dc.relation.isPartOf | BIOTECHNOLOGY AND BIOPROCESS ENGINEERING | - |
dc.citation.title | BIOTECHNOLOGY AND BIOPROCESS ENGINEERING | - |
dc.citation.volume | 25 | - |
dc.citation.number | 4 | - |
dc.citation.startPage | 599 | - |
dc.citation.endPage | 606 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.identifier.kciid | ART002622567 | - |
dc.description.journalClass | 1 | - |
dc.description.isOpenAccess | N | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.description.journalRegisteredClass | kci | - |
dc.relation.journalResearchArea | Biotechnology & Applied Microbiology | - |
dc.relation.journalWebOfScienceCategory | Biotechnology & Applied Microbiology | - |
dc.subject.keywordPlus | ANAEROBIC-DIGESTION | - |
dc.subject.keywordPlus | FATTY-ACID | - |
dc.subject.keywordPlus | BUTANOL PRODUCTION | - |
dc.subject.keywordPlus | MICROORGANISM | - |
dc.subject.keywordAuthor | acyl-CoA transferase | - |
dc.subject.keywordAuthor | alcohol | - |
dc.subject.keywordAuthor | carboxylic acid | - |
dc.subject.keywordAuthor | Megasphaera hexanoica | - |
dc.identifier.url | https://link.springer.com/article/10.1007/s12257-020-0163-x | - |
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