Cognitive Outcomes of Children with Very Low Birth Weight at 3 to 5 Years of Ageopen access
- Authors
- Kim, Hee Sun; Kim, Ee-Kyung; Park, Hyun-Kyung; Ahn, Dong-Hyun; Kim, Mi Jung; Lee, Hyun Ju
- Issue Date
- Jan-2020
- Publisher
- KOREAN ACAD MEDICAL SCIENCES
- Keywords
- Very-Low-Birth-Weight Infants; Cognitive Outcome; Intrauterine Growth Retardation
- Citation
- JOURNAL OF KOREAN MEDICAL SCIENCE, v.35, no.1, pp.1 - 12
- Indexed
- SCIE
SCOPUS
KCI
- Journal Title
- JOURNAL OF KOREAN MEDICAL SCIENCE
- Volume
- 35
- Number
- 1
- Start Page
- 1
- End Page
- 12
- URI
- https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/146412
- DOI
- 10.3346/jkms.2020.35.e4
- ISSN
- 1011-8934
- Abstract
- Background: The cognitive consequences and risk factors based long-term outcome of verylow-birth-weight (VLBW; < 1,500 g) infants in Korea has not been studied. The aim of this study was to determine the influence of perinatal and neonatal risk factors on the cognitive performance of VLBW children at 3 to 5 years of age.
Methods: We enrolled 88 VLBW infants without cystic periventricular leukomalacia for the assessment of their demographic data, cognitive performance, and development of cerebral palsy (CP) at 3 to 5 years of age. Cognitive performance was assessed using the Korean version of the Wechsler Preschool and Primary Scale of Intelligence IV. Growth data were assessed with measurements of weight, height, and head circumference (HC) at the corrected ages of 6, 12, and 18 months, and 3 to 5 years of age.
Results: In the VLBW group, the full-scale intelligence quotient (FSIQ) was 96.1 +/- 15.2 at the mean age of 4.5 years. The incidence rate of CP was 3.4%. Overall, 17% (15/88) of the VLBW children had a below-average FSIQ (< 85). We divided the VLBW children into the abnormal FSIQ group (< 85, n = 15) and the normal FSIQ group (>= 85, n = 73). VLBW children with intrauterine growth retardation (IUGR) was associated with a below-average FSIQ at the mean age of 4.5 years (< 85, 8/15, 53.3% vs. >= 85, 5/73, 6.8%; P < 0.001). After controlling for associated clinical factors, IUGR in the VLBW children was found to be associated with an abnormal FSIQ at the mean age of 4.5 years (P = 0.025). The weight, height, and HC obtained for both groups showed that normal growth was maintained at the mean age of 4.5 years with no significant difference between abnormal and normal FSIQ groups.
Conclusion: Fifteen of 88 (17%) of the VLBW children had a below-average FSIQ (< 85). VLBW with IUGR is associated with poor cognitive outcomes at the mean age of 4.5 years.
- Files in This Item
-
- Appears in
Collections - 서울 의과대학 > 서울 재활의학교실 > 1. Journal Articles
- 서울 의과대학 > 서울 소아청소년과학교실 > 1. Journal Articles
![qrcode](https://api.qrserver.com/v1/create-qr-code/?size=55x55&data=https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/146412)
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.