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Comparison of Characteristics and Survival between Prospective and Retrospective Korea Human Immunodeficiency Virus/Acquired Immune Deficiency Syndrome Cohort Studiesopen access

Authors
Kim, Jun HyoungChoi, YunsuSong, Joon YoungKim, Shin-WooKim, Sang IlKee, Mee-KyungChoi, Bo YoulChoi, Jun Yong
Issue Date
Dec-2019
Publisher
KOREAN SOC CHEMOTHERAPY
Keywords
HIV/AIDS; Cohort study; Survival rates
Citation
INFECTION AND CHEMOTHERAPY, v.51, no.4, pp.393 - 398
Indexed
SCOPUS
KCI
Journal Title
INFECTION AND CHEMOTHERAPY
Volume
51
Number
4
Start Page
393
End Page
398
URI
https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/146668
DOI
10.3947/ic.2019.51.4.393
ISSN
2093-2340
Abstract
By comparing the data of prospectively and retrospectively enrolled cohorts, we evaluated whether the prospective cohort represented all patients in the retrospective cohort. The prospectively enrolled subjects were older and had lower CD4+ T cell counts, higher viral load. In addition, the initial antiretroviral treatment regimen of the prospective cohort consisted of less integrase strand transfer inhibitor-containing regimens. The 20-year survival rate was 51.8% in the prospective cohort and 84.6% in the retrospective cohort, respectively (P = 0.844). This study suggests the prospective cohort study may not represent all patients.
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