Perioperative Hemostatic Management of a Pediatric Patient with Glanzmann Thrombasthenia Undergoing Osteoplastic Craniotomy and Hematoma Removal: A Case Report
- Authors
- Lee, Sung Min; Kim, Kyu Nam; Kim, Soo Yeon
- Issue Date
- Nov-2019
- Publisher
- KARGER
- Keywords
- Glanzmann thrombasthenia; Antifibrinolytic agents; Recombinant factor VIIa
- Citation
- ACTA HAEMATOLOGICA, v.142, no.4, pp.244 - 248
- Indexed
- SCIE
SCOPUS
- Journal Title
- ACTA HAEMATOLOGICA
- Volume
- 142
- Number
- 4
- Start Page
- 244
- End Page
- 248
- URI
- https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/146837
- DOI
- 10.1159/000499362
- ISSN
- 0001-5792
- Abstract
- Glanzmann thrombasthenia is an uncommon hereditary disease that involves an abnormal platelet function leading to complicated hemostatic problems. In situations of anticipated hemorrhage, irradiated apheresed platelets are the first line of treatment. In addition, a combination of recombinant factor VIIa and an antifibrinolytic agent such as tranexamic acid can be utilized to minimize bleeding. Here we are present stable management of a pediatric patient with Glanzmann thrombasthenia admitted for traumatic epidural hematoma removal. Due to the condition of the operation site, some blood loss was unavoidable. However, hemostasis was successfully controlled, and the patient was discharged without additional complications.
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