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Chiral Resolution of Racemic 2-Pyrone Diels-Alder Cycloadduct by Diastereomeric Salt Formation

Authors
Jeon, Tae-HongKang, Hyung-JoonSvirid, AnastasiaLyakhov, AlexanderKovalenko, VitalyCho, Cheon-Gyu
Issue Date
Sep-2019
Publisher
WILEY-V C H VERLAG GMBH
Keywords
3,5-dibromo-2-pyrone; Diels-Alder reaction; Chiral resolution; Diastereomeric salt
Citation
BULLETIN OF THE KOREAN CHEMICAL SOCIETY, v.40, no.9, pp.910 - 913
Indexed
SCIE
SCOPUS
KCI
Journal Title
BULLETIN OF THE KOREAN CHEMICAL SOCIETY
Volume
40
Number
9
Start Page
910
End Page
913
URI
https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/147178
DOI
10.1002/bkcs.11838
ISSN
0253-2964
Abstract
An efficient protocol was developed that allows resolution of racemic bicyclolactone carboxylic acid obtained from the Diels-Alder cycloaddition of 3,5-dibromo-2-pyrone by formation of diastereomeric salts with quinidine and cinchonidine.
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