Clinical characteristics of patients with leiomyoma who undergo surgery after high intensity focused ultrasound (HIFU)open access
- Authors
- Yun Seo Choe; Won Moo Lee; Joong Sub Choi; Jaeman Bae; Jeong Min Eom; Eunsaem Choi
- Issue Date
- Jul-2019
- Publisher
- Korean Society of Obstetrics and Gynecology
- Keywords
- Leiomyoma; High-intensity focused ultrasound ablation; Myomectomy; Hysterectomy
- Citation
- Obstetrics and Gynecology Science, v.62, no.4, pp.258 - 263
- Indexed
- SCOPUS
KCI
- Journal Title
- Obstetrics and Gynecology Science
- Volume
- 62
- Number
- 4
- Start Page
- 258
- End Page
- 263
- URI
- https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/147429
- DOI
- 10.5468/ogs.2019.62.4.258
- ISSN
- 2287-8572
- Abstract
- Objective We evaluated the clinical characteristics of patients who underwent surgery after high intensity focused ultrasound (HIFU) to treat uterine leiomyoma. Methods From June 2016 to September 2017, patients at our hospital who underwent HIFU to treat uterine leiomyoma prior to surgery were enrolled. All patients underwent pelvic magnetic resonance imaging (MRI) before and after HIFU. If 6 months had passed since the last pelvic MRI was performed, imaging was performed again before the operation. Results A total of 12 patients were analyzed. The median age was 45 (range, 28-51) years. The median body mass index was 24.9 (range, 18.1-29.2) kg/m2. The median size of the leiomyoma was 10.1 (range, 7.8-14.0) cm before HIFU, which changed to 8.75 (range, 5.9-14.8) cm after HIFU. The median size increased to 9.1 (range, 5.9-18.0) cm before the operation. Surgery was planned for several reasons, including an increase in the leiomyoma size (n=6), persistent symptoms (n=4), and newly developed lesion (n=2). The median interval between HIFU and surgery was 7 (range, 3-32) months. Ten of the 12 patients underwent laparoscopic surgery, while the others underwent laparotomy; 6 patients also underwent laparoscopic myomectomy, and 4 underwent hysterectomy. Histopathologic findings showed infarction-type necrosis surrounded by granulation tissue with the infiltration of lymphocytes and macrophages in all patients. Conclusion Treatment of leiomyoma with operative procedures should be considered in selected patients with tumor size greater than 10 cm, multiple tumors, and persistent symptoms after HIFU treatment.
- Files in This Item
-
- Appears in
Collections - 서울 의과대학 > 서울 산부인과학교실 > 1. Journal Articles
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.