Combined effects of sulfamethazine and sulfamethoxazole on a freshwater microalga, Scenedesmus obliquus: toxicity, biodegradation, and metabolic fate
DC Field | Value | Language |
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dc.contributor.author | Xiong, Jiu-Qiang | - |
dc.contributor.author | Kim, Sun joon | - |
dc.contributor.author | Kurade, Mayur B. | - |
dc.contributor.author | Govindwar, Sanjay | - |
dc.contributor.author | Abou-Shanab, Reda A. I. | - |
dc.contributor.author | Kim, Jung-Rae | - |
dc.contributor.author | Roh, Hyun-Seog | - |
dc.contributor.author | Khan, Moonis Ali | - |
dc.contributor.author | Jeon, Byong Hun | - |
dc.date.accessioned | 2022-07-09T16:56:05Z | - |
dc.date.available | 2022-07-09T16:56:05Z | - |
dc.date.created | 2021-05-12 | - |
dc.date.issued | 2019-05 | - |
dc.identifier.issn | 0304-3894 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/147903 | - |
dc.description.abstract | This study investigated the environmental effects of two common emerging contaminants, sulfamethazine (SMZ) and sulfamethoxazole (SMX), and their mixture using a green microalga, Scenedesmus obliquus. The calculated EC50 values of SMZ, SMX, and their mixture (11:1 wt/wt) after 96 h were 1.23, 0.12, and 0.89 mg L-1, respectively. The toxicity of the mixture could be better predicted using a concentration addition model than an independent action model. The risk quotients of SMZ, SMX, and their mixture were > 1 during the experiment, indicating their high potential risks on aquatic microorganisms. Despite their toxicity, S. obliquus exhibited 17.3% and 29.3% removal of 0.1 mg L-1 and 0.2 mg L-1 after 11 days of cultivation. The changes of SMZ and SMX removal were observed when combined, which showed a significantly improved removal of SMZ (up to 3.4 folds) with addition of SMX (0.2 mg L-1). The metabolic pathways of SMZ and SMX were proposed according to mass spectroscopic analysis, which showed six metabolites of SMX and seven intermediates of SMZ, formed as a result of ring cleavage, hydroxylation, methylation, nitrosation, and deamination. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | ELSEVIER SCIENCE BV | - |
dc.title | Combined effects of sulfamethazine and sulfamethoxazole on a freshwater microalga, Scenedesmus obliquus: toxicity, biodegradation, and metabolic fate | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Kim, Sun joon | - |
dc.contributor.affiliatedAuthor | Jeon, Byong Hun | - |
dc.identifier.doi | 10.1016/j.jhazmat.2018.07.049 | - |
dc.identifier.scopusid | 2-s2.0-85050317256 | - |
dc.identifier.wosid | 000464483100016 | - |
dc.identifier.bibliographicCitation | JOURNAL OF HAZARDOUS MATERIALS, v.370, pp.138 - 146 | - |
dc.relation.isPartOf | JOURNAL OF HAZARDOUS MATERIALS | - |
dc.citation.title | JOURNAL OF HAZARDOUS MATERIALS | - |
dc.citation.volume | 370 | - |
dc.citation.startPage | 138 | - |
dc.citation.endPage | 146 | - |
dc.type.rims | ART | - |
dc.type.docType | Article; Proceedings Paper | - |
dc.description.journalClass | 1 | - |
dc.description.isOpenAccess | N | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Engineering | - |
dc.relation.journalResearchArea | Environmental Sciences & Ecology | - |
dc.relation.journalWebOfScienceCategory | Engineering, Environmental | - |
dc.relation.journalWebOfScienceCategory | Environmental Sciences | - |
dc.subject.keywordPlus | GREEN-ALGA | - |
dc.subject.keywordPlus | SUBSTRATE INTERACTIONS | - |
dc.subject.keywordPlus | MIXTURES | - |
dc.subject.keywordPlus | ANTIBIOTICS | - |
dc.subject.keywordPlus | SULFONAMIDES | - |
dc.subject.keywordPlus | TRIMETHOPRIM | - |
dc.subject.keywordPlus | CONTAMINANTS | - |
dc.subject.keywordPlus | DEGRADATION | - |
dc.subject.keywordPlus | SALINITY | - |
dc.subject.keywordPlus | REMOVAL | - |
dc.subject.keywordAuthor | Pharmaceutical contaminants sulfamethazine and sulfamethoxazole | - |
dc.subject.keywordAuthor | biodegradation | - |
dc.subject.keywordAuthor | metabolic products | - |
dc.subject.keywordAuthor | microalgae | - |
dc.subject.keywordAuthor | toxicity modeling | - |
dc.identifier.url | https://www.sciencedirect.com/science/article/pii/S030438941830579X?via%3Dihub | - |
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