Sodium excretion and health-related quality of life: the results from the Korea National Health and Nutrition Examination Survey 2010-2011
- Authors
- Choi, Hye Min; Lee, Kyu-Beck; Kim, Hyang; Hyun, Young Youl
- Issue Date
- Nov-2018
- Publisher
- NATURE PUBLISHING GROUP
- Citation
- EUROPEAN JOURNAL OF CLINICAL NUTRITION, v.72, no.11, pp.1490 - 1496
- Indexed
- SCIE
SCOPUS
- Journal Title
- EUROPEAN JOURNAL OF CLINICAL NUTRITION
- Volume
- 72
- Number
- 11
- Start Page
- 1490
- End Page
- 1496
- URI
- https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/148958
- DOI
- 10.1038/s41430-018-0090-5
- ISSN
- 0954-3007
- Abstract
- Background/objectives Little is known about the effect of sodium intake on health-related quality of life (HR-QOL). In this study, we investigated the association between estimated 24-h urine sodium and HR-QOL in Korean adults.
Subjects/methods In this cross-sectional study, we analyzed 10,672 participants from Korea National Health and Nutrition Examination Survey (KNHANES) 2010 similar to 2011. To assess sodium intake, 24-h urine sodium excretion was estimated from random urine sodium and creatinine using the Kawasaki formula. HR-QOL was assessed using EQ-5D (EuroQol five-dimension) index calculated from Korean version of the EQ-5D questionnaire Low HR-QOL was defined as the lowest quartile of the EQ-5D index. Participants were divided into three groups according to their estimated 24-h urine sodium level (low, ˂2.0 g/day; moderate, 2.0 similar to 3.9 g/day; high, ˃4.0 g/day).
Results Adjusted means of EQ-5D index were 0.975, 0.995, and 0.991 in the low, moderate, and high estimated 24-h urine sodium group, respectively (P = 0.003 for low vs. moderate, P = 0.078 for high vs. moderate). In a multiple logistic analysis, the odds ratio (OR) for low EQ-5D index in the low estimated 24-h urine sodium group compared to the moderate group was 1.87 (95% confidence interval (CI), 1.33-2.64; P ˂ 0.001). The OR in the high estimated 24-h urine sodium group compared to the moderate group was 1.09 (95% CI, 0.95-1.24; P = 0.218).
Conclusions Low estimated 24-h urine sodium rather than high estimated 24-h urine sodium was associated with low HR-QOL in representative Korean adults. Further studies are warranted to verify the effect of sodium intake on HR-QOL and the adequate-level sodium restriction in terms of HR-QOL.
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