Treatment of focal dystonia involving multiple muscles with a single injection of botulinum toxin A to 1 muscle A case reportopen access
- Authors
- Lee, Sung Young; Lee, Hyeok Dong; Cho, Young-Shin; Han, Seung Hoon
- Issue Date
- Oct-2018
- Publisher
- LIPPINCOTT WILLIAMS & WILKINS
- Keywords
- botulinum toxin A; distant effect; progressive focal dystonia; single injection
- Citation
- MEDICINE, v.97, no.42, pp.1 - 3
- Indexed
- SCIE
SCOPUS
- Journal Title
- MEDICINE
- Volume
- 97
- Number
- 42
- Start Page
- 1
- End Page
- 3
- URI
- https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/149304
- DOI
- 10.1097/MD.0000000000012785
- ISSN
- 0025-7974
- Abstract
- Rationale
Botulinum toxin A (BTX-A) injection is effective in treating focal dystonia. However, there are no prior reports regarding the treatment of progressive focal dystonia by a single BTX-A injection that affect a distant muscle.
Patient concerns
A 19-year-old male was referred to the rehabilitation clinic with a complaint of involuntary movement in his left big toe. The involuntary movement pattern was initially observed in the abduction direction only; however, it progressed to irregular mixed patterns in the flexion and abduction directions.
Diagnoses
In needle electromyography, abnormal dystonic patterns were observed in the left abductor hallucis (AH), flexor hallucis longus, and flexor hallucis brevis muscles.
Interventions and outcomes
These symptoms resolved with a single BTX-A injection to the AH muscle.
Lessons
In this case, a single BTX-A injection to 1 muscle for treating progressive focal dystonia was effective on a distant noninjected muscle.
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