Metal-Catalyzed Synthesis of Substituted Indoles
- Authors
- Youn, So Won; Ko, Tae Yun
- Issue Date
- Aug-2018
- Publisher
- WILEY-V C H VERLAG GMBH
- Keywords
- C-C bond formation; C-N bond formation; heterocycles; indoles; transition metals
- Citation
- ASIAN JOURNAL OF ORGANIC CHEMISTRY, v.7, no.8, pp.1467 - 1487
- Indexed
- SCIE
SCOPUS
- Journal Title
- ASIAN JOURNAL OF ORGANIC CHEMISTRY
- Volume
- 7
- Number
- 8
- Start Page
- 1467
- End Page
- 1487
- URI
- https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/149576
- DOI
- 10.1002/ajoc.201800290
- ISSN
- 2193-5807
- Abstract
- Indoles are important structural motifs that are commonly found in a diverse array of natural products, pharmaceuticals, and other functional molecules. Consequently, the development of new, more efficient synthetic methods for the construction of substituted indoles continues to be of great importance and considerable interest. Over the past few decades, metal-catalyzed C-C/C-N bond-forming reactions have emerged as a powerful synthetic strategy for heterocyclic synthesis. In this review, we have provided a brief overview of recent advances in the metal-catalyzed synthesis of substituted indoles through the construction of the pyrrole nucleus of indoles, involving the formation of multiple C-C/C-N bonds.
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