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Endogenous Endophthalmitis in the American and Korean Population: An 8-year Retrospective Study

Authors
Cho, HeeyoonShin, Yong UnSiegel, Nicole H.Yu, Hyeong GonSobrin, LuciaPatel, AchalDurand, Marlene L.Miller, Joan W.Husain, Deeba
Issue Date
May-2018
Publisher
TAYLOR & FRANCIS INC
Keywords
Endogenous; endophthalmitis; infectious; vitrectomy
Citation
OCULAR IMMUNOLOGY AND INFLAMMATION, v.26, no.4, pp.496 - 503
Indexed
SCIE
SCOPUS
Journal Title
OCULAR IMMUNOLOGY AND INFLAMMATION
Volume
26
Number
4
Start Page
496
End Page
503
URI
https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/150136
DOI
10.1080/09273948.2016.1195000
ISSN
0927-3948
Abstract
Purpose: To study the clinical features of endogenous endophthalmitis (EE) in sample patient populations from the USA and South Korea over an 8-year period. Methods: We reviewed data from 128 eyes of 60 American and 48 Korean patients diagnosed with EE and compared their clinical characteristics. Results: Fungemia and liver abscess were the most common extraocular infection sources among American (26.7%) and Korean patients (33.3%), respectively. Klebsiella pneumoniae and Candida species were the most common pathogens of EE in the Korean and the American patients, respectively. Endophthalmitis caused by fungi had a better visual prognosis than that caused by bacteria (p = 0.001). Vitrectomy was beneficial for eyes with EE due to virulent bacteria presenting with worse than counting finger vision. Conclusions: The predisposing conditions and responsible organisms for EE vary in different regions of the world. The visual prognosis was strongly influenced by the underlying pathogen.
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COLLEGE OF MEDICINE (DEPARTMENT OF OPHTHALMOLOGY)
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