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Intermediate syndrome after dermal exposure to organophosphate insecticideopen access

Authors
Lee, Su BinRyu, Seung HoPark, Doo YongPark, Jong HoKim, Jee Young
Issue Date
Jan-2018
Publisher
대한임상신경생리학회
Keywords
Organophosphate poisoning; Respiratory insufficiency; Cholinergic
Citation
Annals of Clinical Neurophysiology, v.20, no.1, pp.41 - 43
Indexed
KCI
Journal Title
Annals of Clinical Neurophysiology
Volume
20
Number
1
Start Page
41
End Page
43
URI
https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/150668
DOI
10.14253/acn.2018.20.1.41
ISSN
2508-691X
Abstract
Intermediate syndrome (IMS) typically occurs at 24–96 hours following organophosphate (OP) poisoning, after an acute cholinergic crisis, but before OP-induced delayed polyneuropathy. It is characterized by proximal muscle weakness and respiratory insufficiency, which is a major contributing factor of OP-related morbidity and mortality. We report an atypical IMS case showing rapid-onset ascending paralysis and respiratory disturbance with an acute cholinergic crisis occurring 4–5 days after skin exposure to OP.
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