Can Probability Maps of Swept-Source Optical Coherence Tomography Predict Visual Field Changes in preperimetric Glaucoma?open access
- Authors
- Lee, Won June; Kim, Young Kook; Jeoung, Jin Wook; Park, Ki Ho
- Issue Date
- Dec-2017
- Publisher
- ASSOC RESEARCH VISION OPHTHALMOLOGY INC
- Keywords
- OCT probability map; Preperimetric glaucoma; Structure–function relationship; Swept-source optical coherence tomography; Wide-field
- Citation
- INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, v.58, no.14, pp.6257 - 6264
- Indexed
- SCIE
SCOPUS
- Journal Title
- INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE
- Volume
- 58
- Number
- 14
- Start Page
- 6257
- End Page
- 6264
- URI
- https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/150943
- DOI
- 10.1167/iovs.17-22697
- ISSN
- 0146-0404
- Abstract
- Purpose: To determine the usefulness of swept-source optical coherence tomography (SS-OCT) probability maps in detecting locations with significant reduction in visual field (VF) sensitivity or predicting future VF changes, in patients with classically defined preperimetric glaucoma (PPG).
Methods: Of 43 PPG patients, 43 eyes were followed-up on every 6 months for at least 2 years were analyzed in this longitudinal study. The patients underwent wide-field SS-OCT scanning and standard automated perimetry (SAP) at the time of enrollment. With this wide-scan protocol, probability maps originating from the corresponding thickness map and overlapped with SAP VF test points could be generated. We evaluated the vulnerable VF points with SS-OCT probability maps as well as the prevalence of locations with significant VF reduction or subsequent VF changes observed in the corresponding damaged areas of the probability maps.
Results: The vulnerable VF points were shown in superior and inferior arcuate patterns near the central fixation. In 19 of 43 PPG eyes (44.2%), significant reduction in baseline VF was detected within the areas of structural change on the SS-OCT probability maps. In 16 of 43 PPG eyes (37.2%), subsequent VF changes within the areas of SS-OCT probability map change were observed over the course of the follow-up.
Conclusions: Structural changes on SS-OCT probability maps could detect or predict VF changes using SAP, in a considerable number of PPG eyes. Careful comparison of probability maps with SAP results could be useful in diagnosing and monitoring PPG patients in the clinical setting.
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