접촉성 육아종에서 양성자 펌프 억제제의 치료 효과open accessEffectiveness of Proton Pump Inhibitor in the Treatment of Contact Granuloma
- Other Titles
- Effectiveness of Proton Pump Inhibitor in the Treatment of Contact Granuloma
- Authors
- 김동환; 김건호; 정선민; 송창면; 지용배; 태경
- Issue Date
- Dec-2017
- Publisher
- 대한후두음성언어의학회
- Keywords
- Contact granuloma; Proton pump inhibitor; Laryngopharyngeal reflux; Gastroesophageal reflux; 접촉성 육아종; 양성자 펌프 억제제; 인후두 역류; 위식도 역류
- Citation
- Journal of Korean Society of Laryngology, Phoniatrics and Logopedics, v.28, no.2, pp.123 - 127
- Indexed
- KCI
- Journal Title
- Journal of Korean Society of Laryngology, Phoniatrics and Logopedics
- Volume
- 28
- Number
- 2
- Start Page
- 123
- End Page
- 127
- URI
- https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/150980
- DOI
- 10.22469/jkslp.2017.28.2.123
- ISSN
- 2508-268X
- Abstract
- Background and Objectives
Contact granuloma is granulation tissue that occurs mainly in the vocal process of arytenoid cartilage. Among several etiological factors, gastric acid reflux is known to be an important cause. The aim of this study was to evaluate clinical characteristics of contact granuloma and analyze the effectiveness of proton pump inhibitor in the treatment of contact granuloma.
Materials and Methods
We retrospectively reviewed the medical records of 40 patients who were treated with proton pump inhibitor (PPI) for contact granuloma from January 2011 to December 2015. Reflux finding score (RFS), reflux symptom index (RSI) and size of granuloma were evaluated before and after treatment serially to assess the effectiveness of proton pump inhibitor.
Results
Of 40 patients, 25 patients (62.5%) and 10 patients (25%) showed improvement and partial improvement of granuloma, respectively. Five patients showed no response. The mean times of partial improvement and improvement were 2.08±2.23 months and 4.60±2.77 months, respectively and mean duration of PPI treatment was 6.8±5.2 months.
Conclusion
Proton pump inhibitors is effective in the treatment of contact granuloma.
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