Advances in Computational Human Phantoms and Their Applications in Biomedical Engineering-A Topical Reviewopen access
- Authors
- Kainz, Wolfgang; Neufeld, Esra; Bolch, Wesley E.; Graff, Christian G.; Kim, Chan Hyeong; Kuster, Niels; Lloyd, Bryn; Morrison, Tina; Segars, Paul; Yeom, Yeon Soo; Zankl, Maria; Xu, X. George; Tsui, Benjamin M. W.
- Issue Date
- Jan-2019
- Publisher
- IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC
- Keywords
- Computational modeling; human anatomy; phantoms
- Citation
- IEEE TRANSACTIONS ON RADIATION AND PLASMA MEDICAL SCIENCES, v.3, no.1, pp.1 - 23
- Indexed
- SCOPUS
- Journal Title
- IEEE TRANSACTIONS ON RADIATION AND PLASMA MEDICAL SCIENCES
- Volume
- 3
- Number
- 1
- Start Page
- 1
- End Page
- 23
- URI
- https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/15129
- DOI
- 10.1109/TRPMS.2018.2883437
- ISSN
- 2469-7311
- Abstract
- Over the past decades, significant improvements have been made in the field of computational human phantoms (CHPs) and their applications in biomedical engineering. Their sophistication has dramatically increased. The very first CHPs were composed of simple geometric volumes, e.g., cylinders and spheres, while current CHPs have a high resolution, cover a substantial range of the patient population, have high anatomical accuracy, are poseable, morphable, and are augmented with various details to perform functionalized computations. Advances in imaging techniques and semiautomated segmentation tools allow fast and personalized development of CHPs. These advances open the door to quickly develop personalized CHPs, inherently including the disease of the patient. Because many of these CHPs are increasingly providing data for regulatory submissions of various medical devices, the validity, anatomical accuracy, and availability to cover the entire patient population is of utmost importance. This paper is organized into two main sections: the first section reviews the different modeling techniques used to create CHPs, whereas the second section discusses various applications of CHPs in biomedical engineering. Each topic gives an overview, a brief history, recent developments, and an outlook into the future.
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