Tumor necrosis and complete resection has significant impacts on survival in patients with limited-stage upper aerodigestive tract NK/T cell lymphoma
DC Field | Value | Language |
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dc.contributor.author | Song, Moo-Kon | - |
dc.contributor.author | Chung, Joo-Seop | - |
dc.contributor.author | Yhim, Ho-Young | - |
dc.contributor.author | Lim, Sung-Nam | - |
dc.contributor.author | Kim, Seong-Jang | - |
dc.contributor.author | Han, Yeon-Hee | - |
dc.contributor.author | Shim, Hye-Kyung | - |
dc.contributor.author | Jung, Sung-Hoon | - |
dc.contributor.author | Lee, Je-Jung | - |
dc.contributor.author | Yang, Deok-Hwan | - |
dc.date.accessioned | 2022-07-13T05:53:48Z | - |
dc.date.available | 2022-07-13T05:53:48Z | - |
dc.date.created | 2021-05-12 | - |
dc.date.issued | 2017-10 | - |
dc.identifier.issn | 1949-2553 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/151521 | - |
dc.description.abstract | Tumor necrosis (TN) is associated with worse prognosis in several solid cancers. Whether TN predicts poor outcome in natural killer cell / T cell lymphoma (NKTCL) is unclear. We investigated the clinical impact of TN on survival and other novel prognostic parameters in upper aero-digestive tract (UAT) NKTCL of 100 patients with limited stage. TN was significantly associated with poor performance status (p = 0.049), high Korean Prognostic Index score (p = 0.024), high C-reactive protein/albumin ratio (p = 0.003), higher maximum standard uptake value on positron emission tomography/computed tomography (PET/CT) (p = 0.008) and higher metabolic tumor volume (MTV) on PET/CT (p < 0.001). In univariate and multivariate analyses, progression-free survival and overall survival were independently associated with High MTV status (p = 0.001, p = 0.032), TN (p = 0.018, p = 0.009), local tumor invasiveness (p = 0.007, p = 0.035), complete resection (p = 0.020, p = 0.028) and regional lymph node involvement (p < 0.001, p < 0.001). TN and complete resection are concluded to be novel independent prognostic factors in patients with UAT NKTCL. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | IMPACT JOURNALS LLC | - |
dc.title | Tumor necrosis and complete resection has significant impacts on survival in patients with limited-stage upper aerodigestive tract NK/T cell lymphoma | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Song, Moo-Kon | - |
dc.identifier.doi | 10.18632/oncotarget.18107 | - |
dc.identifier.scopusid | 2-s2.0-85030452506 | - |
dc.identifier.wosid | 000412111300096 | - |
dc.identifier.bibliographicCitation | ONCOTARGET, v.8, no.45, pp.79337 - 79346 | - |
dc.relation.isPartOf | ONCOTARGET | - |
dc.citation.title | ONCOTARGET | - |
dc.citation.volume | 8 | - |
dc.citation.number | 45 | - |
dc.citation.startPage | 79337 | - |
dc.citation.endPage | 79346 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.isOpenAccess | Y | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Oncology | - |
dc.relation.journalResearchArea | Cell Biology | - |
dc.relation.journalWebOfScienceCategory | Oncology | - |
dc.relation.journalWebOfScienceCategory | Cell Biology | - |
dc.subject.keywordPlus | NECK-CANCER PATIENTS | - |
dc.subject.keywordPlus | LOCALLY ADVANCED HEAD | - |
dc.subject.keywordPlus | NASAL-TYPE | - |
dc.subject.keywordPlus | T-CELL | - |
dc.subject.keywordPlus | CLINICAL DIFFERENCES | - |
dc.subject.keywordPlus | PROGNOSTIC MARKER | - |
dc.subject.keywordPlus | LUNG-CANCER | - |
dc.subject.keywordPlus | FDG-PET | - |
dc.subject.keywordPlus | VOLUME | - |
dc.subject.keywordPlus | CARCINOMA | - |
dc.subject.keywordAuthor | extranodal natural killer/T-cell lymphoma | - |
dc.subject.keywordAuthor | tumor necrosis | - |
dc.subject.keywordAuthor | complete resection | - |
dc.subject.keywordAuthor | prognosis | - |
dc.identifier.url | https://www.oncotarget.com/article/18107/text/ | - |
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