Real-time Triple-modal Photoacoustic, Ultrasound, and Magnetic Resonance Fusion Imaging of Humans
- Authors
- Park, Sara; Jang, Jongseong; Kim, Jeesu; Kim, Young Soo; Kim, Chulhong
- Issue Date
- Sep-2017
- Publisher
- IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC
- Keywords
- Image registration; medical imaging; optical imaging; optical-tracking based navigation system; ultrasound
- Citation
- IEEE TRANSACTIONS ON MEDICAL IMAGING, v.36, no.9, pp.1912 - 1921
- Indexed
- SCIE
SCOPUS
- Journal Title
- IEEE TRANSACTIONS ON MEDICAL IMAGING
- Volume
- 36
- Number
- 9
- Start Page
- 1912
- End Page
- 1921
- URI
- https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/151705
- DOI
- 10.1109/TMI.2017.2696038
- ISSN
- 0278-0062
- Abstract
- Imaging that fuses multiple modes has become a useful tool for diagnosis and therapeutic monitoring. As a next step, real-time fusion imaging has attracted interest as for a tool to guide surgery. One widespread fusion imaging technique in surgery combines real-time ultrasound (US) imaging and pre-acquired magnetic resonance (MR) imaging. However, US imaging visualizes only structural information with relatively low contrast. Here, we present a photoacoustic (PA), US, and MR fusion imaging system which integrates a clinical PA and US imaging system with an optical tracking-based navigation subsystem. Through co-registration of pre-acquired MR and real-time PA/US images, overlaid PA, US, and MR images can be concurrently displayed in real time. We successfully acquired fusion images from a phantom and a blood vessel in a human forearm. This fusion imaging can complementarily delineate the morphological and vascular structure of tissues with good contrast and sensitivity, has a well established user interface, and can be flexibly integrated with clinical environments. As a novel fusion imaging, the proposed triple-mode imaging can provide comprehensive image guidance in real time, and can potentially assist various surgeries.
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