Can robot-assisted laparoscopic radical prostatectomy (RALP) be performed very soon after biopsy?
- Authors
- Jo, Jung Ki; Oh, Jong Jin; Lee, Sangchul; Jeong, Seong Jin; Hong, Sung Kyu; Byun, Seok-Soo; Lee, Sang Eun
- Issue Date
- Apr-2017
- Publisher
- SPRINGER
- Keywords
- Robot-assisted radical prostatectomy; Interval; Prostate biopsy
- Citation
- WORLD JOURNAL OF UROLOGY, v.35, no.4, pp.605 - 612
- Indexed
- SCIE
SCOPUS
- Journal Title
- WORLD JOURNAL OF UROLOGY
- Volume
- 35
- Number
- 4
- Start Page
- 605
- End Page
- 612
- URI
- https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/152573
- DOI
- 10.1007/s00345-016-1893-4
- ISSN
- 0724-4983
- Abstract
- Purpose
To identify the perioperative and oncological impact of different intervals between biopsy and robot-assisted laparoscopic radical prostatectomy (RALP) for localized prostate cancer.
Methods
All consecutive patients with localized prostate cancer who underwent RALP with primary curative intent in January 2008–July 2014 in a large tertiary hospital were enrolled in this retrospective cohort study. The patients were divided into groups according to whether the biopsy–RALP interval was ≤2, ≤4, ≤6, or >6 weeks. Estimated blood loss and operating room time were surrogates for surgical difficulty. Surgical margin status and continence at the 1 year were surrogates for surgical efficacy. Biochemical recurrence (BCR) was defined as two consecutive postoperative prostate serum antigen values of ≥0.2 ng/ml.
Results
Of the 1446 enrolled patients, the biopsy–RALP interval was ≤2, ≤4, ≤6, and >6 weeks in 145 (10 %), 728 (50.3 %), 1124 (77.7 %), and 322 (22.3 %) patients, respectively. The >6 week group had a significantly longer mean operation time than the ≤2, ≤4, and ≤6 week groups. The groups did not differ significantly in terms of estimated blood loss or surgical margin status. Kaplan–Meier analysis showed that interval did not significantly affect postoperative BCR-free survival. Multivariable Cox proportional hazards model analysis showed that interval duration was not an independent predictor of BCR (≤2 vs. >2 weeks, HR = 0.859, p = 0.474; ≤4 vs. >4 weeks, HR = 1.029, p = 0.842; ≤6 vs. >6 weeks, HR = 0.84, p = 0.368).
Conclusion
Performing RALP within 2, 4, or 6 weeks of biopsy does not appear to adversely influence surgical difficulty or efficacy or oncological outcomes.
- Files in This Item
-
Go to Link
- Appears in
Collections - 서울 의과대학 > 서울 비뇨의학교실 > 1. Journal Articles
![qrcode](https://api.qrserver.com/v1/create-qr-code/?size=55x55&data=https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/152573)
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.