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Cognitive Functions: Human vs. Animal-4:1 Advantage |-FAM72-SRGAP2-|

Authors
Nguyen Thi Thanh HoKim, Pok-SonKutzner, ArneHeese, Klaus
Issue Date
Apr-2017
Publisher
Humana Press, Inc.
Keywords
Ape; Brain; Evolution; Homo; Neuron; Phylogenetic tree; Synapse; Taxonomy
Citation
Journal of Molecular Neuroscience, v.61, no.4, pp 603 - 606
Pages
4
Indexed
SCIE
SSCI
SCOPUS
Journal Title
Journal of Molecular Neuroscience
Volume
61
Number
4
Start Page
603
End Page
606
URI
https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/152582
DOI
10.1007/s12031-017-0901-5
ISSN
0895-8696
1559-1166
Abstract
With the advent of computational genomics, an intensive search is underway for unique biomarkers for Homo sapiens that could be used to differentiate taxa within the Hominoidea, in particular to distinguish Homo from the apes (Pan, Gorilla, Pongo, and Hylobates) and species or subspecies within the genus Homo (H. sapiens, H. heidelbergensis, H. neanderthalensis, H. erectus, and the Denisovans). Here, we suggest that the |-FAM72-SRGAP2-| (family with sequence similarity 72/SLIT-ROBO Rho GTPase activating protein 2) gene pair is a unique molecular biomarker for the genus Homo that could also help to place Australopithecus at its most appropriate place within the phylogenetic tree and may explain the distinctive higher brain cognitive functions of humans.
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GRADUATE SCHOOL OF BIOMEDICAL SCIENCE AND ENGINEERING (DEPARTMENT OF BIOMEDICAL SCIENCE)
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