Comparative characteristics of quantitative indexes for F-18-FDG uptake and metabolic volume in sequentially obtained PET/MRI and PET/CT
DC Field | Value | Language |
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dc.contributor.author | Lee, Soo Jin | - |
dc.contributor.author | Paeng, Jin Chul | - |
dc.contributor.author | Goo, Jin Mo | - |
dc.contributor.author | Lee, Jeong Min | - |
dc.contributor.author | Cheon, Gi Jeong | - |
dc.contributor.author | Lee, Dong Soo | - |
dc.contributor.author | Chung, June-Key | - |
dc.contributor.author | Kang, Keon Wook | - |
dc.date.accessioned | 2022-07-14T12:26:27Z | - |
dc.date.available | 2022-07-14T12:26:27Z | - |
dc.date.created | 2021-05-11 | - |
dc.date.issued | 2017-04 | - |
dc.identifier.issn | 0143-3636 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/152656 | - |
dc.description.abstract | Purpose The purpose of this study was to compare quantitative indexes for fluorine-18 fluorodeoxyglucose uptake and metabolic volume between PET/MRI and PET/CT. Patients and methods Sixty-six patients with solid tumors (32 with lung cancer and 34 with pancreatic cancer) who underwent sequential fluorine-18 fluorodeoxyglucose PET/MRI and PET/CT were retrospectively enrolled. On PET images, maximum and peak standardized uptake values (SUVmax and SUVpeak, respectively), and maximum tumor-to-liver ratio (TLRmax) were measured. Metabolic tumor volume (MTV) and total-lesion glycolysis (TLG) with margin thresholds of 50% SUVmax and SUV 2.5 (MTV50%, MTV2.5; TLG50%, TLG2.5, respectively) were compared between PET/MRI and PET/CT, with patients classified into two groups using imaging protocol (the PET/MRI-first and PET/CT-first groups). Results There were significant correlations of all tested indexes between PET/MRI and PET/CT (r=0.867–0.987, P<0.001). SUVmax and SUVpeak were lower on PET/MRI regardless of imaging protocol (P<0.001 in the PET/MRI-first group). In contrast, TLRmax exhibited reverse results between the PET/MRI-first and PET/CT-first groups. MTV50% and TLG values varied between PET/MRI and PET/CT, as well as between the PET/MRI-first and PET/CT-first groups. However, MTV2.5 was relatively robust against imaging protocol and modality. Conclusion There are significant correlations of the quantitative indexes between PET/MRI and PET/CT. However, uptake indexes of SUVmax and SUVpeak are lower on PET/MRI than on PET/CT, and volumetric indexes of MTV50% and TLG values also exhibited significant differences. It may be suggested that TLRmax and MTV2.5 are relatively more appropriate indexes than others when PET/MRI and PET/CT are used interchangeably. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | Lippincott Williams & Wilkins Ltd. | - |
dc.title | Comparative characteristics of quantitative indexes for F-18-FDG uptake and metabolic volume in sequentially obtained PET/MRI and PET/CT | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Lee, Soo Jin | - |
dc.identifier.doi | 10.1097/MNM.0000000000000655 | - |
dc.identifier.scopusid | 2-s2.0-85014061045 | - |
dc.identifier.wosid | 000398205600009 | - |
dc.identifier.bibliographicCitation | Nuclear Medicine Communications, v.38, no.4, pp.333 - 339 | - |
dc.relation.isPartOf | Nuclear Medicine Communications | - |
dc.citation.title | Nuclear Medicine Communications | - |
dc.citation.volume | 38 | - |
dc.citation.number | 4 | - |
dc.citation.startPage | 333 | - |
dc.citation.endPage | 339 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.isOpenAccess | N | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Radiology, Nuclear Medicine & Medical Imaging | - |
dc.relation.journalWebOfScienceCategory | Radiology, Nuclear Medicine & Medical Imaging | - |
dc.subject.keywordPlus | STANDARDIZED UPTAKE VALUE | - |
dc.subject.keywordPlus | NORMAL ORGAN-TISSUES | - |
dc.subject.keywordPlus | WHOLE-BODY PET/CT | - |
dc.subject.keywordPlus | CLINICAL-EXPERIENCE | - |
dc.subject.keywordPlus | PROGNOSTIC VALUE | - |
dc.subject.keywordPlus | LESION DETECTION | - |
dc.subject.keywordPlus | CANCER | - |
dc.subject.keywordPlus | PERFORMANCE | - |
dc.subject.keywordPlus | FDG | - |
dc.subject.keywordAuthor | cancer | - |
dc.subject.keywordAuthor | correlation study | - |
dc.subject.keywordAuthor | MRI | - |
dc.subject.keywordAuthor | PET | - |
dc.subject.keywordAuthor | tumor volume | - |
dc.identifier.url | https://journals.lww.com/nuclearmedicinecomm/Fulltext/2017/04000/Comparative_characteristics_of_quantitative.9.aspx | - |
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