Clinicoepidemiological features of melasma in Korean patients at five university hospitals: A cross-sectional multicenter study한국인 기미환자의 5개 대학병원 다기관 임상역학연구
- Other Titles
- 한국인 기미환자의 5개 대학병원 다기관 임상역학연구
- Authors
- Lee, Mi Hye; Noh, Tai Kyung; Lee, Jong Hee; Roh, Mi Ryung; Na, Jung Im; Jung, Eui Chang; Ko, Joo Yeon; Chang, Sung Eun
- Issue Date
- Aug-2016
- Publisher
- Korean Dermatological Association
- Keywords
- Aggravating factors; Korean; Melasma; Questionnaire
- Citation
- Korean Journal of Dermatology, v.54, no.7, pp.532 - 537
- Indexed
- SCOPUS
KCI
- Journal Title
- Korean Journal of Dermatology
- Volume
- 54
- Number
- 7
- Start Page
- 532
- End Page
- 537
- URI
- https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/154153
- ISSN
- 0494-4739
- Abstract
- Background: Melasma is a common acquired hypcrpigmentation disorder that predominantly affects the face. It frequently occurs in women with darker skin types and severely impacts quality of life. Objective: To characterize the clinicoepidemiological features and triggering or aggravating factors of melasma in Korean patients. Methods: This cross-sectional study was conducted at the dermatology clinics of five university hospitals in Korea. Between January 2011 and August 2012, 411 patients with melasma completed a questionnaire about the clinical and aggravating factors associated with their melasma. Results: The study population consisted of 400 women and 11 men aged 22 73 years (mean age, 42.8±9.92 years). Triggering or aggravating factors were sun exposure (68.4%), pregnancy (27.0%), and emotional stress (24.8%). Interestingly, 61.1% of patients complained of sensitive/inflammatory features such as erythema, itching, and a stinging sensation. Dryness was the most common aggravating factor, followed by erythema/redness and itching/stinging. Concomitant pigmentary disorders included post-inflammatory hypcrpigmentation in 15.1% of patients, followed by pigmented contact dermatitis, and acquired bilateral nevus of Ota-like macules. Conclusion: It is well known that sun exposure and hormonal changes are the most common triggers of melasma; however, sensitive/inflammatory features may aggravate melasma in East Asian patients. Therefore, these individual and racial differences should be considered in the prevention and treatment of melasma. (Korean J Dermatol 2016;54(7) :532 537).
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