무증상 혹은 재발성 급성 부비동염의 원인으로 작용하는 생물구: 2예Bioballs Causing Asymptomatic or Recurrent Acute Rhinosinusitis: Two Cases
- Other Titles
- Bioballs Causing Asymptomatic or Recurrent Acute Rhinosinusitis: Two Cases
- Authors
- 김홍대; 이동원; 표주연; 오영하; 조석현
- Issue Date
- May-2016
- Publisher
- 대한비과학회
- Keywords
- Biofilm; Bacteria; Pseudomonas; Rhinosinusitis; Maxillary sinus; 생물막; 세균; 녹농균; 비부비동염; 상악동
- Citation
- Journal of Rhinology, v.23, no.1, pp.55 - 59
- Indexed
- KCI
- Journal Title
- Journal of Rhinology
- Volume
- 23
- Number
- 1
- Start Page
- 55
- End Page
- 59
- URI
- https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/154646
- DOI
- 10.18787/jr.2016.23.1.55
- ISSN
- 1229-1498
- Abstract
- A variety of intrinsic and extrinsic factors have been studied to explain the pathogenesis of rhinosinusitis. Recently biofilms are emerging as an important cause. Biofilms are highly organized structures composed of a protective extracellular matrix and bacterial colonies, and provide the means for bacterial survival and virulence. Biofilms are known to be associated with intractable cases of rhinosinusitis and antibiotic resistance. Patients diagnosed with biofilm-related rhinosinusitis tend to suffer more severe disease that those without biofilms. Biofilm severity can also influence the prognosis of rhinosinusitis. We present two cases of pseudomonas-induced macroscopic biofilms (bioballs) of the maxillary sinuses. These bioballs cause intractable chronic rhinosinusitis as well, but unlike traditional biofilms, they can be surgically removed by endoscopy, and thus have a better prognosis than traditional biofilms. This is the first report of visible biofilms (bioballs) found in the maxillary sinuses.
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