피부 전이를 보인 목척수의 조직구육종Histiocytic Sarcoma of the Cervical Spinal Cord with Secondary Involvement of the Skin
- Other Titles
- Histiocytic Sarcoma of the Cervical Spinal Cord with Secondary Involvement of the Skin
- Authors
- 박형권; 최현석; 김영균; 오영하; 유희준; 김정수
- Issue Date
- Mar-2016
- Publisher
- 대한피부과학회
- Keywords
- Histiocytic sarcoma; True histiocytic lymphoma; Malignant histiocytosis
- Citation
- 대한피부과학회지, v.54, no.3, pp.199 - 202
- Indexed
- SCOPUS
KCI
- Journal Title
- 대한피부과학회지
- Volume
- 54
- Number
- 3
- Start Page
- 199
- End Page
- 202
- URI
- https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/154942
- ISSN
- 0494-4739
- Abstract
- Histiocytic sarcoma is a rare, lymphohematopoietic malignant tumor comprised of tumor cells with the morphological and immunophenotypic features of mature histiocytes. A 35-year-old man presented with a disseminated histiocytic sarcoma that first occurred in the spinal cord and metastasized to the skin and lymph nodes. The tumor cells of the primary histiocytic sarcoma of the spinal cord were very large epithelioid cells with abundant eosinophilic cytoplasms and large, round-to-oval nuclei. In contrast, the metastatic histiocytic sarcoma of the skin was composed of relatively small polygonal cells with well-defined cell borders and high N/C (nucleus/cytoplasm) ratios.
Immunohistochemically, both tumors were diffusely positive for histiocyte-associated antigens; but negative for epithelial, melanocyte, lymphoid, and dendritic cell antigens. It is important to recognize the morphological features and immunohistochemical characteristics of metastatic cells in order to ensure accurate diagnoses.
- Files in This Item
-
Go to Link
- Appears in
Collections - 서울 의과대학 > 서울 피부과학교실 > 1. Journal Articles
- 서울 의과대학 > 서울 병리학교실 > 1. Journal Articles
![qrcode](https://api.qrserver.com/v1/create-qr-code/?size=55x55&data=https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/154942)
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.