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The cooperative FeCl3/DDQ system for the regioselective synthesis of 3-arylindoles from beta-monosubstituted 2-alkenylanilines

Authors
Jang, Su SanYoun, So Won
Issue Date
Feb-2016
Publisher
ROYAL SOC CHEMISTRY
Citation
ORGANIC & BIOMOLECULAR CHEMISTRY, v.14, no.7, pp.2200 - 2204
Indexed
SCIE
SCOPUS
Journal Title
ORGANIC & BIOMOLECULAR CHEMISTRY
Volume
14
Number
7
Start Page
2200
End Page
2204
URI
https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/155151
DOI
10.1039/c6ob00074f
ISSN
1477-0520
Abstract
A highly regioselective synthesis of 3-arylindoles by using the cooperative FeCl3/DDQ system has been developed. This new protocol represents an attractive route for the synthesis of 3-arylindoles from readily accessible non-indole precursors, beta-arylsubstituted 2-styrylanilines, using an inexpensive catalyst and oxidant. Noteworthy is the unique synergetic and synergistic effect of FeCl3 and DDQ on the 1,2-aryl migratory process.
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