VARIABILITY IN INTERPRETATION OF ULTRASOUND ELASTOGRAPHY AND GRAY-SCALE ULTRASOUND IN ASSESSING THYROID NODULES
- Authors
- Koh, Jieun; Moon, Hee Jung; Park, Jeong Seon; Kim, Soo Jin; Kim, Ha Yan; Kim, Eun-Kyung; Kwak, Jin Young
- Issue Date
- Jan-2016
- Publisher
- ELSEVIER SCIENCE INC
- Keywords
- Elastography; Thyroid nodule; Inter-observer variability; Ultrasound; Diagnosis
- Citation
- ULTRASOUND IN MEDICINE AND BIOLOGY, v.42, no.1, pp.51 - 59
- Indexed
- SCIE
SCOPUS
- Journal Title
- ULTRASOUND IN MEDICINE AND BIOLOGY
- Volume
- 42
- Number
- 1
- Start Page
- 51
- End Page
- 59
- URI
- https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/155319
- DOI
- 10.1016/j.ultrasmedbio.2015.08.005
- ISSN
- 0301-5629
- Abstract
- The aim of this study was to validate inter-observer variability for strain ultrasound elastography (USE) and to compare the diagnostic performance of a combination of gray-scale ultrasound (US) and USE with that of gray-scale US. Three observers from different institutions evaluated gray-scale US images and USE video files of 443 cytopathologically proven benign or malignant thyroid nodules over a 3-mo period. Interobserver variability did not statistically differ between USE using the Asteria criteria and gray-scale US; however, USE using the Rago criteria had the lowest inter-observer agreement (p < 0.043). For all three observers, sensitivity was increased by adding USE to gray-scale US (81.3%-88.3%, 75.4%-85.4%) compared with gray-scale US (70.4%-80.8%). Specificity was decreased by adding USE to gray-scale US (51.7%-59.1%, 59.1%-73.9%) compared with gray-scale US (69.0%-82.8%). USE and gray-scale US had comparable inter-observer variability. However, on addition of USE to gray-scale US, the additional diagnostic yield was limited compared with that of gray-scale US alone.
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