The relationship between brain-derived neurotrophic factor and cognitive functions in alcohol-dependent patients: a preliminary study
DC Field | Value | Language |
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dc.contributor.author | Han, Changwoo | - |
dc.contributor.author | Bae, Hwallip | - |
dc.contributor.author | Won, Sung-Doo | - |
dc.contributor.author | Roh, Sung won | - |
dc.contributor.author | Kim, Dai-Jin | - |
dc.date.accessioned | 2022-07-15T20:57:44Z | - |
dc.date.available | 2022-07-15T20:57:44Z | - |
dc.date.created | 2021-05-14 | - |
dc.date.issued | 2015-09 | - |
dc.identifier.issn | 1744-859X | - |
dc.identifier.uri | https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/156316 | - |
dc.description.abstract | Background: As a neurotoxic substance, alcohol can induce neurodegenesis in the brain. Alcohol-dependent patients' cognitive functioning can be affected by chronic alcohol use. In addition, brain-derived neurotrophic factor (BDNF) is known to reflect the status of neuroadaptive changes. The purpose of this study was to investigate the relationship between cognitive functions and BDNF in alcohol-dependent patients. Methods: The subjects were 39 alcohol-dependent patients. BDNF was measured using an enzyme-linked immunosorbent assay kit. We examined clinical features and administered the Korean version of Alcohol Dependence Scale. We also used the Consortium to Establish a Registry for Alzheimer's Disease (CERAD) to measure cognitive functioning. Then, we determined the relationships between BDNF and various parts of the CERAD. Results: The performance of alcohol-dependent patients proved stable in most parts of the CERAD. Within the different parts of the CERAD, only Trail Making Test B correlated with BDNF. Trail Making Test specifically assesses executive functions. Conclusions: BDNF might play an important role in the detection of neurocognitive function among individuals with alcohol dependence. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | BIOMED CENTRAL LTD | - |
dc.title | The relationship between brain-derived neurotrophic factor and cognitive functions in alcohol-dependent patients: a preliminary study | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Roh, Sung won | - |
dc.identifier.doi | 10.1186/s12991-015-0065-z | - |
dc.identifier.scopusid | 2-s2.0-84960374431 | - |
dc.identifier.wosid | 000361651600001 | - |
dc.identifier.bibliographicCitation | ANNALS OF GENERAL PSYCHIATRY, v.14, no.1, pp.1 - 10 | - |
dc.relation.isPartOf | ANNALS OF GENERAL PSYCHIATRY | - |
dc.citation.title | ANNALS OF GENERAL PSYCHIATRY | - |
dc.citation.volume | 14 | - |
dc.citation.number | 1 | - |
dc.citation.startPage | 1 | - |
dc.citation.endPage | 10 | - |
dc.type.rims | ART | - |
dc.type.docType | 정기학술지(Article(Perspective Article포함)) | - |
dc.description.journalClass | 1 | - |
dc.description.isOpenAccess | Y | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | ssci | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Psychiatry | - |
dc.relation.journalWebOfScienceCategory | Psychiatry | - |
dc.subject.keywordPlus | NEUROPSYCHOLOGICAL DEFICITS | - |
dc.subject.keywordPlus | ETHANOL-CONSUMPTION | - |
dc.subject.keywordPlus | SERUM-LEVELS | - |
dc.subject.keywordPlus | BDNF | - |
dc.subject.keywordPlus | SCHIZOPHRENIA | - |
dc.subject.keywordPlus | DEPRESSION | - |
dc.subject.keywordPlus | PROBDNF | - |
dc.subject.keywordPlus | CONSORTIUM | - |
dc.subject.keywordPlus | ADDICTION | - |
dc.subject.keywordPlus | ESTABLISH | - |
dc.subject.keywordAuthor | Alcohol dependence | - |
dc.subject.keywordAuthor | Cognitive function | - |
dc.subject.keywordAuthor | Brain-derived neurotrophic factor | - |
dc.identifier.url | https://annals-general-psychiatry.biomedcentral.com/articles/10.1186/s12991-015-0065-z | - |
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