Randomized controlled trial of sodium phosphate tablets vs polyethylene glycol solution for colonoscopy bowel cleansing
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Jung, Yoon Suk | - |
dc.contributor.author | Lee, Chang Kyun | - |
dc.contributor.author | Kim, Hyo Jong | - |
dc.contributor.author | Eun, Chang Soo | - |
dc.contributor.author | Han, Dong Soo | - |
dc.contributor.author | Park, Dong Il | - |
dc.date.accessioned | 2022-07-16T02:17:30Z | - |
dc.date.available | 2022-07-16T02:17:30Z | - |
dc.date.created | 2021-05-11 | - |
dc.date.issued | 2014-11 | - |
dc.identifier.issn | 1007-9327 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/158783 | - |
dc.description.abstract | AIM: To compare efficacy, patient compliance, acceptability, satisfaction, safety, and adenoma detection rate of sodium phosphate tablets (NaP, CLICOLONTM) to a standard 4 L polyethylene glycol (PEG) solution for bowel cleansing for adults undergoing colonoscopy. METHODS: In this multicenter, randomized, prospective, investigator-blind study, the relatively young (19-60 years) healthy outpatients without comorbidity were randomly assigned to one of two arms. All colonoscopy were scheduled in the morning. The NaP group was asked to take 4 tablets, 5 times the evening before and 4 tablets, 3 times early on the morning of the colonos-copy. The PEG group was asked to ingest 2 L of solution the evening before and 2 L early in the morning of the procedure. Adequacy of bowel preparation was scored using the Boston bowel preparation scale. RESULTS: No significant differences were observed between the NaP group (n = 158) and PEG group (n = 162) in bowel cleansing quality (adequate preparation 93.0% vs 92.6%, p = 0.877), patient compliance (p = 0.228), overall adverse events (63.3% vs 69.1%, p = 0.269), or adenoma detection rate (34.8% vs 35.2%, p = 0.944). Patient acceptability, satisfaction, and patient rating of taste were higher in the NaP group than in the PEG group (p < 0.001). CONCLUSION: NaP tablets, compared with PEG solution, produced equivalent colon cleansing, did not cause more side effects, and had better patient acceptability and satisfaction in the relatively young (age < 60 years) healthy individuals without comorbidity. An oral tablet formulation could make bowel preparation less burdensome, resulting in greater patient participation in screening programs. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | BAISHIDENG PUBLISHING GROUP INC | - |
dc.title | Randomized controlled trial of sodium phosphate tablets vs polyethylene glycol solution for colonoscopy bowel cleansing | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Eun, Chang Soo | - |
dc.contributor.affiliatedAuthor | Han, Dong Soo | - |
dc.identifier.doi | 10.3748/wjg.v20.i42.15845 | - |
dc.identifier.scopusid | 2-s2.0-84912087294 | - |
dc.identifier.wosid | 000345115400040 | - |
dc.identifier.bibliographicCitation | WORLD JOURNAL OF GASTROENTEROLOGY, v.20, no.42, pp.15845 - 15851 | - |
dc.relation.isPartOf | WORLD JOURNAL OF GASTROENTEROLOGY | - |
dc.citation.title | WORLD JOURNAL OF GASTROENTEROLOGY | - |
dc.citation.volume | 20 | - |
dc.citation.number | 42 | - |
dc.citation.startPage | 15845 | - |
dc.citation.endPage | 15851 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.isOpenAccess | N | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Gastroenterology & Hepatology | - |
dc.relation.journalWebOfScienceCategory | Gastroenterology & Hepatology | - |
dc.subject.keywordPlus | COLORECTAL-CANCER | - |
dc.subject.keywordPlus | PEG SOLUTION | - |
dc.subject.keywordPlus | PATIENT ACCEPTANCE | - |
dc.subject.keywordPlus | PARALLEL-GROUP | - |
dc.subject.keywordPlus | RENAL-FAILURE | - |
dc.subject.keywordPlus | BLINDED TRIAL | - |
dc.subject.keywordPlus | 4-L PEG | - |
dc.subject.keywordPlus | HYPERPHOSPHATEMIA | - |
dc.subject.keywordPlus | EFFICACY | - |
dc.subject.keywordPlus | QUALITY | - |
dc.subject.keywordAuthor | Sodium phosphate tablets | - |
dc.subject.keywordAuthor | Polyethylene glycol | - |
dc.subject.keywordAuthor | Colonoscopy | - |
dc.subject.keywordAuthor | Bowel preparation | - |
dc.identifier.url | https://www.wjgnet.com/1007-9327/full/v20/i42/15845.htm | - |
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.
222, Wangsimni-ro, Seongdong-gu, Seoul, 04763, Korea+82-2-2220-1365
COPYRIGHT © 2021 HANYANG UNIVERSITY.
Certain data included herein are derived from the © Web of Science of Clarivate Analytics. All rights reserved.
You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.