Robot‐assisted radical prostatectomy in the Korean population: A 5‐year propensity‐score matched comparative analysis versus open radical prostatectomy
- Authors
- Koo, Kyo Chul; Tuliao, Patrick; Yoon, YOUNG EUN; Chung, Byung Ha; Hong, Sung Joon; Yang, Seung Choul; Rha, Koon Ho
- Issue Date
- Aug-2014
- Publisher
- WILEY-BLACKWELL
- Keywords
- prostate cancer; prostatectomy; robotics; treatment outcome
- Citation
- INTERNATIONAL JOURNAL OF UROLOGY, v.21, no.8, pp.781 - 785
- Indexed
- SCIE
SCOPUS
- Journal Title
- INTERNATIONAL JOURNAL OF UROLOGY
- Volume
- 21
- Number
- 8
- Start Page
- 781
- End Page
- 785
- URI
- https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/159323
- DOI
- 10.1111/iju.12447
- ISSN
- 0919-8172
- Abstract
- Objectives: To compare the oncological outcomes of robot-assisted laparoscopic radical prostatectomy with those of open radical prostatectomy in contemporary Korean prostate cancer patients.
Methods: From a group of 1172 patients consisting of 592 (50.5%) robot-assisted laparoscopic radical prostatectomy and 580 (49.5%) open radical prostatectomy cases carried out between 1992 and 2008, 175 robot-assisted laparoscopic radical prostatectomy cases were matched with an equal number of open radical prostatectomy cases by propensity scoring based on patient age, preoperative prostate-specific antigen, biopsy Gleason score and clinical tumor stage. Competing-risks survival analyses were used to evaluate oncological outcomes, including rates of positive surgical margin, biochemical-recurrence, adjuvant therapy, cancer-specific survival, overall survival and metastasis-free survival during the mean follow up of 58.4 months.
Results: Positive surgical margin rates were comparable between robot-assisted laparoscopic radical prostatectomy and open radical prostatectomy cohorts (19.4% vs 21.8%), with comparable rates for all pathological stages and risk subgroups. Positive surgical margin rates according to location were comparable, with the apical margin being the most common location. Robot-assisted laparoscopic radical prostatectomy recovered higher lymph node yields compared with open radical prostatectomy (12.5 vs 3.8; P < 0.001). The robot-assisted laparoscopic radical prostatectomy and the open radical prostatectomy groups showed equal oncological outcomes regarding 5-year biochemical recurrence-free survival (log-rank P = 0.651), metastasis-free survival (log-rank P = 0.876), cancer-specific survival (log-rank P = 0.076) and overall survival (log-rank P = 0.648), respectively. Between groups, there was no difference in the rate of adjuvant therapy, time to first adjuvant therapy failure or in the rate of subsequent secondary treatment.
Conclusions: Robot-assisted laparoscopic radical prostatectomy represents an effective surgical approach for the treatment of prostate cancer in the Korean population, as it provides equivalent oncological outcomes to open radical prostatectomy.
- Files in This Item
-
Go to Link
- Appears in
Collections - 서울 의과대학 > 서울 비뇨의학교실 > 1. Journal Articles
![qrcode](https://api.qrserver.com/v1/create-qr-code/?size=55x55&data=https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/159323)
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.