한국인 루푸스 임상연구의 현재와 미래The Present and Future of Clinical Research for Korean Lupus Patients
- Other Titles
- The Present and Future of Clinical Research for Korean Lupus Patients
- Authors
- 김담; 조수경; 성윤경
- Issue Date
- Aug-2014
- Publisher
- 대한류마티스학회
- Keywords
- Lupus erythematosus; Systemic; Clinical study; Korean
- Citation
- 대한류마티스학회지, v.21, no.4, pp.223 - 223
- Indexed
- KCI
- Journal Title
- 대한류마티스학회지
- Volume
- 21
- Number
- 4
- Start Page
- 223
- End Page
- 223
- URI
- https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/159327
- DOI
- 10.4078/jrd.2014.21.2.54
- ISSN
- 2093-940X
- Abstract
- Systemic lupus erythematosus (SLE) is considered to be the prototype of systemic autoimmune disease because it involves the most immune cells and it can affect all organs of the human body. Despite the advances in understanding the etiology and pathogenesis of SLE, a sobering fact is that only a few drugs have been licensed for its treatment. This may be associated with the difficulties in performing clinical trials due to its diverse clinical manifestations and comorbidities of SLE, as well as difficulties in determining the disease outcome. To determine the natural course and drug response of SLE patients, various observational studies have been conducted in Western countries. However, in Korea, sufficiently powered prospective clinical studies are scarce. In this review, we conducted a systematic review to be aware of the current status of clinical studies in Korean SLE patients. Identifying the topics for clinical studies that have been performed helps determine how the clinical research should be conducted for Korean SLE patients.
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