Changes in the seroprevalence of IgG anti-hepatitis A virus between 2001 and 2013: experience at a single center in Koreaopen access
- Authors
- Chung, Sung Jun; Kim, Tae Yeob; Kim, Sun Min; Roh, Min; Yu, Mi Yeon; Lee, Jung Hoon; Oh, Chang Kyo; Lee, Eun Young; Lee, Seung; Jeon, Yong Cheol; Yoo, Kyo Sang; Sohn, Joo Hyun
- Issue Date
- Jun-2014
- Publisher
- The Korean Association for the Study of the Liver
- Keywords
- Hepatitis A virus; IgG Anti-HAV; Seroprevalence
- Citation
- Clinical and molecular hepatology, v.20, no.2, pp.162 - 167
- Indexed
- SCOPUS
KCI
- Journal Title
- Clinical and molecular hepatology
- Volume
- 20
- Number
- 2
- Start Page
- 162
- End Page
- 167
- URI
- https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/159891
- DOI
- 10.3350/cmh.2014.20.2.162
- ISSN
- 2287-2728
- Abstract
- "BACKGROUND/AIMS: The incidence of symptomatic hepatitis A reportedly increased among 20- to 40-year-old Korean during the late 2000s. Vaccination against hepatitis A was commenced in the late 1990s and was extended to children aged <10 years. In the present study we analyzed the changes in the seroprevalence of IgG anti-hepatitis A virus (HAV) over the past 13 years.METHODS: Overall, 4903 subjects who visited our hospital between January 2001 and December 2013 were studied. The seroprevalence of IgG anti-HAV was analyzed according to age and sex. In addition, the seroprevalence of IgG anti-HAV was compared among 12 age groups and among the following time periods: early 2000s (2001-2003), mid-to-late 2000s (2006-2008), and early 2010s (2011-2013). The chi-square test for trend was used for statistical analysis.RESULTS: The seroprevalence of IgG anti-HAV did not differ significantly between the sexes. Furthermore, compared to the seroprevalence of IgG anti-HAV in the early 2000s and mid-to-late 2000s, that in the early 2010s was markedly increased among individuals aged 1-14 years and decreased among those aged 25-44 years (P<0.01). We also found that the seroprevalence of IgG anti-HAV in individuals aged 25-44 years in the early 2010s was lower than that in the early 2000s and mid-to-late 2000s.CONCLUSIONS: The number of symptomatic HAV infection cases in Korea is decreasing, but the seroprevalence of IgG anti-HAV is low in the active population.
- Files in This Item
-
- Appears in
Collections - 서울 의과대학 > 서울 내과학교실 > 1. Journal Articles
![qrcode](https://api.qrserver.com/v1/create-qr-code/?size=55x55&data=https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/159891)
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.