Side-chain Prediction and Computational Protein Design Problems
- Authors
- Kim, Deok Soo; Ryu, Joonghyun
- Issue Date
- Mar-2014
- Publisher
- 한국구조생물학회
- Keywords
- .
- Citation
- Biodesign, v.2, no.1, pp.26 - 37
- Indexed
- KCI
- Journal Title
- Biodesign
- Volume
- 2
- Number
- 1
- Start Page
- 26
- End Page
- 37
- URI
- https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/160456
- ISSN
- 2288-6982
- Abstract
- Protein is fundamental for life and thus protein design has been one of the hottest research issues since a couple ofdecades ago and computational approach has been developed with some significant design cases with experimentalverification. One of the fundamental building blocks of computational protein design is to predict side-chain conformationof backbone structure. This paper first reviews prior efforts of computationally predicting sidechains of a given backboneand then reviews computational protein design efforts based on side-chain prediction. The paper views computationalprotein design problem as three categories: Redesign, De novo design of Type I, and De novo design of Type II. Some wellknowncomputer programs and algorithms related with computational protein design are also reviewed.
- Files in This Item
-
Go to Link
- Appears in
Collections - 서울 공과대학 > 서울 기계공학부 > 1. Journal Articles
![qrcode](https://api.qrserver.com/v1/create-qr-code/?size=55x55&data=https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/160456)
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.