Role of metastasectomy on overall survival of patients with metastatic gastric canceropen access
- Authors
- Yang, Seung Wook; Kim, Min Gyu; Lee, Ju Hee; Kwon, Sung Joon
- Issue Date
- Dec-2013
- Publisher
- The Korean Gastric Cancer Association.
- Keywords
- Distant metastasis; Gastric cancer; Metastasectomy; Overall survival
- Citation
- Journal of Gastric Cancer, v.13, no.4, pp.226 - 231
- Indexed
- SCOPUS
KCI
OTHER
- Journal Title
- Journal of Gastric Cancer
- Volume
- 13
- Number
- 4
- Start Page
- 226
- End Page
- 231
- URI
- https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/161247
- DOI
- 10.5230/jgc.2013.13.4.226
- ISSN
- 2093-582X
- Abstract
- Purpose: The role of metastasectomy has been debatable and unclear in the treatment for patients with metastatic gastric cancer. Therefore, this study was designed to evaluate the role of metastasectomy on the overall survival of these patients. Materials and Methods: In 2,406 patients who underwent gastrectomy for gastric cancer between 1998 and 2010, 188 (7.8%) patients had their first surgery for metastatic gastric cancer. To minimize the bias of systemic chemotherapy, 99 patients who received postoperative chemotherapy (fewer than 2 cycles) were excluded. The primary gastrectomy or metastasectomy had not been enforced in the following cases. Patients with far advanced peritoneal dissemination, multiple liver and lung metastasis (more than 2), and a poor general condition (Eastern Cooperative Oncology Group>2) were excluded. Based on the metastasectomy, the patients were classified into two groups, gastrectomy with metastasectomy and gastrectomy only group. Results: There was no significant difference between both groups in clinicopathological characteristics except for the mean age (P=0.047). The univariate analysis for overall survival show statistical significances in metastasectomy (P=0.026), distal gastrectomy (P=0.047), and combined resection of another organ (P=0.047) group. With a multivariate analysis, metastasectomy was a significant factor in patient survival after surgery (odds ratio 1.679; P=0.034). Conclusions: Based on our results, we assume that a detailed strategy for surgery is needed to improve the overall survival of patients with metastatic gastric cancer. Therefore, we suggest that a metastasectomy can help prolong overall survival in some patients with metastatic gastric cancer.
- Files in This Item
-
- Appears in
Collections - 서울 의과대학 > 서울 외과학교실 > 1. Journal Articles
![qrcode](https://api.qrserver.com/v1/create-qr-code/?size=55x55&data=https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/161247)
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.