Anxiety and depression propensities in patients with acute toxic liver injury
- Authors
- Suh, Jeong Ill; Sakong, Jeong Kyu; Lee, Kwan; Lee, Yong Kook; Park, Jeong Bae; Kim, Dong Joon; Seo, Yeon Seok; Lee, Jae Dong; Ko, Soon Young; Lee, Byung Seok; Kim, Seok Hyun; Kim, Byung Seok; Kim, Young Seok; Lee, Heon Ju; Kim, In Hee; Sohn, Joo Hyun; Kim, Tae Yeob; Ahn, Byung Min
- Issue Date
- Dec-2013
- Publisher
- BAISHIDENG PUBLISHING GROUP INC
- Keywords
- Liver injury; Herb; Toxic; Anxiety; Depression
- Citation
- WORLD JOURNAL OF GASTROENTEROLOGY, v.19, no.47, pp.9069 - 9076
- Indexed
- SCIE
SCOPUS
- Journal Title
- WORLD JOURNAL OF GASTROENTEROLOGY
- Volume
- 19
- Number
- 47
- Start Page
- 9069
- End Page
- 9076
- URI
- https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/161353
- DOI
- 10.3748/wjg.v19.i47.9069
- ISSN
- 1007-9327
- Abstract
- AIM: To investigate anxiety and depression propensities in patients with toxic liver injury. METHODS: The subjects were divided into three groups: a healthy control group (Group 1, n = 125), an acute non-toxic liver injury group (Group 2, n = 124), and a group with acute toxic liver injury group caused by non-commercial herbal preparations (Group 3, n = 126). These three groups were compared and evaluated through questionnaire surveys and using the Hospital Anxiety-Depression Scale (HADS), Beck Anxiety Inventory (BAI), Beck Depression Inventory (BDI), and the hypochondriasis scale. RESULTS: The HADS anxiety subscale was 4.9 +/- 2.7, 5.0 +/- 3.0 and 5.6 +/- 3.4, in Groups 1, 2, and 3, respectively. The HADS depression subscale in Group 3 showed the most significant score (5.2 +/- 3.2, 6.4 +/- 3.4 and 7.2 +/- 3.4 in Groups 1, 2, and 3, respectively) (P < 0.01 vs Group 1, P < 0.05 vs Group 2). The BAI and BDI in Group 3 showed the most significant score (7.0 +/- 6.3 and 6.9 +/- 6.9, 9.5 +/- 8.6 and 8.8 +/- 7.3, 10.7 +/- 7.2 and 11.6 +/- 8.5 in Groups 1, 2, and 3, respectively) (BAI: P < 0.01 vs Group 1, P < 0.05 vs Group 2) (BDI: P < 0.01 vs Group 1 and 2). Group 3 showed a significantly higher hypochondriasis score (8.2 +/- 6.0, 11.6 +/- 7.5 and 13.1 +/- 6.5 in Groups 1, 2, and 3, respectively) (P < 0.01 vs Group 1, P < 0.05 vs Group 2). CONCLUSION: Psychological factors that present vulnerability to the temptation to use alternative medicines, such as herbs and plant preparations, are important for understanding toxic liver injury.
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