Cognitive impairment, depression, comorbidity of the two and associated factors among the early sixties in a rural Korean communityopen access
- Authors
- Park, Boyoung; Park, Jonghan; Jun, Jae Kwan
- Issue Date
- Nov-2013
- Publisher
- PUBLIC LIBRARY SCIENCE
- Citation
- PLOS ONE, v.8, no.11, pp.1 - 6
- Indexed
- SCIE
SSCI
SCOPUS
- Journal Title
- PLOS ONE
- Volume
- 8
- Number
- 11
- Start Page
- 1
- End Page
- 6
- URI
- https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/161439
- DOI
- 10.1371/journal.pone.0079460
- ISSN
- 1932-6203
- Abstract
- This study was conducted to investigate the prevalence of cognitive impairment, depression, and comorbidity of the two conditions and related factors in subjects aged in early 60s. This cross-sectional study included 3,174 inhabitants aged 60-64 years old in a rural area of Korea. Cognitive function was evaluated by the Korean version of the Mini-Mental State Examination (MMSE-K), and depression was measured using the short form of the Geriatric Depression Scale (GDS-15). The overall prevalence of cognitive impairment (MMSE-K <= 24) was 17.4%, that of depression was 26.0% (GDS-15 >= 8), and the comorbidity was 7.1%. Female gender, living with one housemate, and high GDS-15 score were significantly associated with increased cognitive impairment. Employment status and more years of schooling were associated with a decreased probability of cognitive impairment. Increased depression was significantly associated with bereavement and receiving benefits from the Medical Aid Program. Employed status, more years of schooling, and higher MMSE-K scores were significantly associated with decreased depression. The risk of comorbidity was associated with bereavement and receipt of Medical Aid benefits (odds ratio[OR], 1.85; 95% confidence interval[CI], 1.26-2.71; OR, 5.02; 95% CI, 2.37-10.63; respectively). Employment and more years of schooling were associated with a lower risk of comorbidity (OR, 0.46; 95% CI, 0.34-0.62, P-trend <0.01). The correlated factors for cognitive impairment, depression, and comorbidity of the two conditions were similar, and employment status and years of schooling were associated with all three conditions.
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