Dual-energy CT to detect recurrent HCC after TACE: Initial experience of color-coded iodine CT imaging
- Authors
- Lee, Jeong-Ah; Jeong, Woo Kyoung; Kim, Yongsoo; Song, Soon-Young; Kim, Jinoo; Heo, Jeong Nam; Park, Choong Ki
- Issue Date
- Apr-2013
- Publisher
- ELSEVIER IRELAND LTD
- Keywords
- Dual-energy CT; Iodine map; Hepatocellular carcinoma; Transcatheter arterial chemoembolization (TACE); Recurrence; Diagnostic performance
- Citation
- EUROPEAN JOURNAL OF RADIOLOGY, v.82, no.4, pp.569 - 576
- Indexed
- SCIE
SCOPUS
- Journal Title
- EUROPEAN JOURNAL OF RADIOLOGY
- Volume
- 82
- Number
- 4
- Start Page
- 569
- End Page
- 576
- URI
- https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/163135
- DOI
- 10.1016/j.ejrad.2012.11.014
- ISSN
- 0720-048X
- Abstract
- Objectives: To evaluate the feasibility of diagnosing recurrence of HCC after TACE color-coded iodine CT (CICT) based on arterial phase scans obtained by a dual-energy CT (DECT) scanner. Methods: A CICT scan was acquired from an iodine map after applying material decomposition of the liver tissue and setting a threshold attenuation level for viable tumors. Two radiologists reviewed both conventional and CICT sets in 31 patients who had a history of TACE for HCC. The performances in detecting local tumor progression (LTP) were evaluated by alternative free-response receiver operating characteristics. The rate of uncertain diagnosis and interobserver agreement of the diagnosis were explored. Additionally, the reading time and radiation dose were also investigated. Results: The mean figures of merit of the conventional and CICT sets for LTP were 0.818 and 0.847, respectively (p = 0.459). The rate of uncertain diagnosis was significantly decreased in CICT sets (34.5% vs. 0%), and interobserver agreement was improved (k = 0.527 vs. 0.718). On the CICT set, mean reading time was reduced by 49 s and mean radiation dose was also decreased by 18.3% when replacing the non-contrast CT with CICT. Conclusions: CICT is comparable to conventional liver CT protocol in demonstrating viable HCCs, while it allows a reduction in radiation dose.
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