Clinical value of metabolic tumor volume by PET/CT in extranodal natural killer/T cell lymphoma
DC Field | Value | Language |
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dc.contributor.author | Song, Moo Kon | - |
dc.contributor.author | Chung, Joo-Seop | - |
dc.contributor.author | Shin, Ho-Jin | - |
dc.contributor.author | Moon, Joon-Ho | - |
dc.contributor.author | Ahn, Jae-Sook | - |
dc.contributor.author | Lee, Ho-Sup | - |
dc.contributor.author | Lee, Sang-Min | - |
dc.contributor.author | Lee, Gyeong-Won | - |
dc.contributor.author | Kim, Seong-Jang | - |
dc.contributor.author | Lee, Seok-Mo | - |
dc.date.accessioned | 2022-07-16T11:37:59Z | - |
dc.date.available | 2022-07-16T11:37:59Z | - |
dc.date.created | 2021-05-13 | - |
dc.date.issued | 2013-01 | - |
dc.identifier.issn | 0145-2126 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/163592 | - |
dc.description.abstract | This study investigated whether metabolic tumor volume (MTV) by PET/CT as indicator of extent of lymphoma burden would be a prognostic factor in stage IE/IIE extranodal natural killer/T cell lymphoma (ENKTCL). Eighty patients with stage I-E/IIE ENKTCL in the upper aerodigestive tract underwent PET/CT at diagnosis were enrolled and 32 patients received upfront radiotherapy (RTx). MTV was measured on PET/CT images by the extranodal region above SUV, 2.5. Receiver operating curve analyses indicated that an MTV of 35.2 cm(3) was the ideal cut-off to distinguish between low and high MTV groups. Clinical outcomes were compared according to several prognostic factors (age, stage, high performance status [PS], high International Prognostic Index, elevated lactate dehydrogenase [LDH], local tumor invasiveness [LTI], high MTV and up-front RT). High PS, elevated LDH, LTI, high MTV and upfront RT were associated with survivals. In multivariate analysis, high MTV (PFS, HR = 4.170, 95% CI = 1.714-10.147, p = 0.002; OS, HR = 4.102, 95% CI = 1.617-10.408, p = 0.003) and up-front RT (PFS, HR = 0.410, 95% CI = 0.178-0.946, p = 0.037; OS, HR = 0.365, 95% CI = 0.152-0.872, p = 0.023) were significant independent prognostic factors. Upfront RTx and extent of tumor burden, as measured by the MTV, had significant prognostic value in patients with ENKTCL. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | PERGAMON-ELSEVIER SCIENCE LTD | - |
dc.title | Clinical value of metabolic tumor volume by PET/CT in extranodal natural killer/T cell lymphoma | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Song, Moo Kon | - |
dc.identifier.doi | 10.1016/j.leukres.2012.09.011 | - |
dc.identifier.scopusid | 2-s2.0-84870907232 | - |
dc.identifier.wosid | 000312196800011 | - |
dc.identifier.bibliographicCitation | LEUKEMIA RESEARCH, v.37, no.1, pp.58 - 63 | - |
dc.relation.isPartOf | LEUKEMIA RESEARCH | - |
dc.citation.title | LEUKEMIA RESEARCH | - |
dc.citation.volume | 37 | - |
dc.citation.number | 1 | - |
dc.citation.startPage | 58 | - |
dc.citation.endPage | 63 | - |
dc.type.rims | ART | - |
dc.type.docType | 정기학술지(Article(Perspective Article포함)) | - |
dc.description.journalClass | 1 | - |
dc.description.isOpenAccess | N | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Oncology | - |
dc.relation.journalResearchArea | Hematology | - |
dc.relation.journalWebOfScienceCategory | Oncology | - |
dc.relation.journalWebOfScienceCategory | Hematology | - |
dc.subject.keywordPlus | NON-HODGKINS-LYMPHOMAS | - |
dc.subject.keywordPlus | NASAL-TYPE | - |
dc.subject.keywordPlus | PROGNOSTIC-FACTORS | - |
dc.subject.keywordPlus | T-CELL | - |
dc.subject.keywordPlus | ANGIOCENTRIC LYMPHOMA | - |
dc.subject.keywordPlus | FDG-PET | - |
dc.subject.keywordPlus | RADIOTHERAPY | - |
dc.subject.keywordPlus | CAVITY | - |
dc.subject.keywordPlus | CLASSIFICATION | - |
dc.subject.keywordPlus | UTILITY | - |
dc.subject.keywordAuthor | Lymphoma | - |
dc.subject.keywordAuthor | Positron emission tomography | - |
dc.subject.keywordAuthor | Radiotherapy | - |
dc.identifier.url | https://www.sciencedirect.com/science/article/pii/S0145212612003840?via%3Dihub | - |
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