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Quantitative analysis of the fate of gold nanocages in vitro and in vivo after uptake by U87-MG tumor cellsopen access
- Authors
- Cho, E.C.; Zhang, Y.; Cai, X.; Moran, C.M.; Wang, L.V.; Xia, Y.
- Issue Date
- Jan-2013
- Publisher
- John Wiley & Sons Ltd.
- Keywords
- biological activity; cell uptake; drug delivery; gold; nanoparticles
- Citation
- Angewandte Chemie - International Edition, v.52, no.4, pp.1152 - 1155
- Indexed
- SCIE
SCOPUS
- Journal Title
- Angewandte Chemie - International Edition
- Volume
- 52
- Number
- 4
- Start Page
- 1152
- End Page
- 1155
- ISSN
- 1433-7851
- Abstract
- Not always equal: When a mother cell that contains Au nanocages divides, the nanoparticles are unequally distributed between the two daughter cells. This unequal distribution of nanoparticles as well as their clearance from the cells (see picture) is quantitatively analyzed both in vitro and in vivo using two-photon microscopy and photoacoustic microscopy, respectively.
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Related Researcher
- Cho, Eun Chul
- COLLEGE OF ENGINEERING (DEPARTMENT OF CHEMICAL ENGINEERING)