Polyuria with the concurrent manifestation of Central Diabetes Insipidus (CDI) & type 2 Diabetes Mellitus (DM)open access
- Authors
- Shin, Hyun-Jong; Kim, Jae-Ha; Yi, Joo-Hark; Han, Sang-Woong; Kim, Ho-Jung
- Issue Date
- Dec-2012
- Publisher
- 전해질고혈압연구회
- Keywords
- Central diabetes insipidus; Polyuria; Type 2 diabetes mellitus; Water deprivation test
- Citation
- Electrolyte and Blood Pressure, v.10, no.1, pp.26 - 30
- Indexed
- SCOPUS
KCI
OTHER
- Journal Title
- Electrolyte and Blood Pressure
- Volume
- 10
- Number
- 1
- Start Page
- 26
- End Page
- 30
- URI
- https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/164020
- DOI
- 10.5049/EBP.2012.10.1.26
- ISSN
- 1738-5997
- Abstract
- We report a rare case of the concurrent manifestation of central diabetes insipidus (CDI) and type 2 diabetes mellitus (DM). A 56 year-old man was diagnosed as a type 2 DM on the basis of hyperglycemia with polyuria and polydipsia at a local clinic two months ago and started an oral hypoglycemic medication, but resulted in no symptomatic improvement at all. Upon admission to the university hospital, the patient's Initial fasting blood sugar level was 140 mg/dL, and he showed polydipsic and polyuric conditions more than 8 L urine/day. Despite the hyperglycemia controlled with metformin and diet, his symptoms persisted. Further investigations including water deprivation test confirmed the coexisting CDI of unknown origin, and the patient's symptoms including an intense thirst were markedly improved by desmopressin nasal spray (10 μg/day). The possibility of a common origin of CDI and type 2 DM is raised in a review of the few relevant adult cases in the literature.
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