Nasal and Exhaled Nitric Oxide in Allergic Rhinitisopen access
- Authors
- Lee, Keon Jung; Cho, Seok Hyun; Lee, Seung Hwan; Tae, Kyung; Yoon, Ho Joo; Kim, Sang Heon; Jeong, Jin Hyeok
- Issue Date
- Dec-2012
- Publisher
- KOREAN SOC OTORHINOLARYNGOL
- Keywords
- Nitirc oxide; Nasal nitric oxide; Exhaled nitric oxide; Allergic rhinitis; Asthma
- Citation
- CLINICAL AND EXPERIMENTAL OTORHINOLARYNGOLOGY, v.5, no.4, pp.228 - 233
- Indexed
- SCIE
SCOPUS
KCI
OTHER
- Journal Title
- CLINICAL AND EXPERIMENTAL OTORHINOLARYNGOLOGY
- Volume
- 5
- Number
- 4
- Start Page
- 228
- End Page
- 233
- URI
- https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/164094
- DOI
- 10.3342/ceo.2012.5.4.228
- ISSN
- 1976-8710
- Abstract
- Objectives. The primary aim of this study was to assess whether one can use levels of nasal nitric oxide (nNO) and exhaled nitric oxide (eNO) as a means of evaluation in allergic rhinitis. Methods. We used a chemiluminescence analyzer to measure nNO and eNO in normal controls (n = 34) and allergic rhinitis patients (n = 35), and compared these measurements with various parameters of clinical symptoms and laboratory data. Results. Mean nNO (389 +/- 119 ppb) in allergic rhinitis patients was significantly higher than normal controls (276 +/- 88 ppb). Without asthma, mean eNO (64.8 +/- 55.9 ppb) in allergic rhinitis patients was significantly higher than normal controls (33.0 +/- 24.0 ppb). In the persistent allergic rhinitis group, eNO concentration was significantly higher, while nNO concentration was significantly lower than the intermittent group. Conclusion. We can use nNO and eNO levels for evaluation of allergic rhinitis. However, we should consider the fact that nNO levels can be reduced, when symptoms are severe and long-lasting. Additionally, in allergic rhinitis, eNO can be elevated without asthma.
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