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Effect of nano-structured polymer surfaces on the phenotype control of preosteoblasts

Authors
Yeon, Soo-JeongLee, Jin WookLee, Jae-WonRhim, TaiyounKwark, Young-JeKim, Seung HyunLee, Kuen Yong
Issue Date
Nov-2012
Publisher
한국고분자학회
Citation
Macromolecular Research, v.20, no.11, pp 1205 - 1208
Pages
4
Indexed
SCI
SCIE
SCOPUS
KCI
Journal Title
Macromolecular Research
Volume
20
Number
11
Start Page
1205
End Page
1208
URI
https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/164305
DOI
10.1007/s13233-012-0165-4
ISSN
1598-5032
2092-7673
Abstract
The surface nano-structure of polymer matrices is one of the important parameters for controlling cell phenotype and function in tissue engineering. Nano-structured polymer surfaces were produced via self-assembly of polystyrene-b-poly(ethylene oxide)/dode-cylbenzenesulfonic acid complex systems. Polystyrene domain size and center-to-center distance between the domains under 100 nm strongly influenced the adhesion, proliferation, and differentiation of preosteoblasts cultured on the nano-polymer surfaces, irrespective of the same total domain area.
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