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A fatal case of hepatitis B virus (HBV) reactivation during long-term, very-low-dose steroid treatment in an inactive HBV carrier.open access
- Authors
- Bae, Joong Ho; Sohn, Joo Hyun; Lee, Hye Soon; Park, Hye Sun; Hyun, Yil Sik; Kim, Tae Yeob; Eun, Chang Soo; Jeon, Yong Cheol; Han, Dong Soo
- Issue Date
- Oct-2012
- Publisher
- The Korean Association for the Study of the Liver
- Keywords
- Hepatitis B virus; Liver failure; Steroids; Virus activation
- Citation
- Clinical and molecular hepatology, v.18, no.2, pp.225 - 228
- Indexed
- SCOPUS
KCI
- Journal Title
- Clinical and molecular hepatology
- Volume
- 18
- Number
- 2
- Start Page
- 225
- End Page
- 228
- ISSN
- 2287-2728
- Abstract
- Hepatitis B virus (HBV) may be reactivated after chemotherapy or immunosuppressive therapy, and therefore administration of antiviral agents before such treatment is recommended. Most reported cases of reactivation are associated with high doses of immunosuppressive agents or combination therapy. We present a case of a previously inactive HBV carrier with an acute severe flare-up during a long-term, very-low-dose (2.5 mg/day) steroid treatment for rheumatoid arthritis. We suggest that even a minimal dose of single-regimen oral steroid can cause reactivation of indolent, inactive HBV.
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Collections - 서울 의과대학 > 서울 내과학교실 > 1. Journal Articles
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Related Researcher
- Eun, Chang soo
- 서울 의과대학 (DEPARTMENT OF INTERNAL MEDICINE)