교모세포종에서의 단기간내 신경아교육종성 재발 -증례보고 및 고찰-A Rapid Gliosarcomatous Recurrence of the Glioblastoma - Case Report and Review of the Literatures -
- Other Titles
- A Rapid Gliosarcomatous Recurrence of the Glioblastoma - Case Report and Review of the Literatures -
- Authors
- 송대효; 김충현; 정진환; 김재민
- Issue Date
- Sep-2012
- Publisher
- 대한뇌종양학회
- Keywords
- Glioblastoma; Secondary gliosarcoma; Recurrence
- Citation
- 대한뇌종양학회지, v.11, no.2, pp.154 - 157
- Indexed
- OTHER
- Journal Title
- 대한뇌종양학회지
- Volume
- 11
- Number
- 2
- Start Page
- 154
- End Page
- 157
- URI
- https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/164677
- ISSN
- 1598-530X
- Abstract
- A gliosarcoma represents a biphasic tissue pattern with altering areas displaying glial and mesenchymal differentiation and accounts for approximately 2% of all glioblastomas. We present a rare case with rapid gliosarcomatous recurrence of the glioblastoma which have been taken a complete resection and concomitant chemoradiotheraphy (CCRT). A 54-year-old female presented with sudden onset of the headache. Magnetic resonance (MR) imaging showed a well-demarcated, enhanced lesion in the right fronto-temporal area. She received grossly total tumor resection followed by radiotherapy and chemotherapy. Her postoperative course was uneventful. However, brain MR images at 6 months after surgery demonstrated a newly developed, nodular lesion in the tumor bed. At 9 months after surgery, the follow-up MR images revealed the increased size of tumor in the right fronto-temporo-parietal area with invasion into the right lateral ventricle. She received sur-gery again, and pathological studies revealed a recurrent glioblastoma with the component of gliosarcoma. The authors report and discuss an uncommon case with gliosarcomatous recurrence of glioblastoma after surgery and CCRT.
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