Tumor size as a prognostic factor in gastric cancer patientopen access
- Authors
- Im, Won Jin; Kim, Min Gyu; Ha, Tae Kyung; Kwon, Sung Joon
- Issue Date
- Sep-2012
- Publisher
- The Korean Gastric Cancer Association
- Keywords
- Gastric cancer; Prognosis; Tumor size
- Citation
- Journal of Gastric Cancer, v.12, no.3, pp.164 - 172
- Indexed
- SCOPUS
KCI
OTHER
- Journal Title
- Journal of Gastric Cancer
- Volume
- 12
- Number
- 3
- Start Page
- 164
- End Page
- 172
- URI
- https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/164727
- DOI
- 10.5230/jgc.2012.12.3.164
- ISSN
- 2093-582X
- Abstract
- Purpose: The purpose of this study is to investigate the prognostic significance of tumor size for 5-year survival rate in patients with gastric cancer. Materials and Methods: A total of 1,697 patients with gastric cancer, who underwent potentially curative gastrectomy, were evaluated. Patients were divided into 4 groups as follows, according to the median size of early and advanced gastric cancer, respectively: small early gastric cancer (tumor size ≤3 cm), large early gastric cancer (tumor size >3 cm), small advanced gastric cancer (tumor size ≤ 6 cm), and large advanced gastric cancer (tumor size >6 cm). The prognostic value of tumor size for 5-year survival rate was investigated. Results: In a univariate analysis, tumor size is a significant prognostic factor in advanced gastric cancer, but not in early gastric cancer. Multivariate analysis showed that tumor size is an independent prognostic factor for 5-year survival rate in advanced gastric cancer (P=0.003, hazard ratio=1.372, 95% confidence interval=1.115~1.690). When advanced gastric cancer is subdivided into 2 groups, according to serosa invasion: Group 1; serosa negative (T2 and T3, 7th AJCC), and Group 2; serosa positive (T4a and T4b, 7th AJCC), tumor size is an independent prognostic factor in Group 1 (P=0.011, hazard ratio=1.810, 95% confidence interval=1.149~2.852) and in Group 2 (P=0.033, hazard ratio=1.288, 95% confidence interval=1.020~1.627), respectively. Conclusions: Tumor size is an independent prognostic factor in advanced gastric cancer irrespective of the serosa invasion, but not in early gastric cancer.
- Files in This Item
-
- Appears in
Collections - 서울 의과대학 > 서울 외과학교실 > 1. Journal Articles
![qrcode](https://api.qrserver.com/v1/create-qr-code/?size=55x55&data=https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/164727)
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.