A Facile Synthesis of Discoidal Lipid Bilayer Nanostructure by Association of a Cationic Amphiphilic Polyelectrolyte
- Authors
- Cho, Eun Chul
- Issue Date
- Jul-2012
- Publisher
- KOREAN CHEMICAL SOC
- Keywords
- Lipid bilayer nanostructures; Cationic amphiphilic polymer; Hollow hemisphere; Disc
- Citation
- BULLETIN OF THE KOREAN CHEMICAL SOCIETY, v.33, no.7, pp.2187 - 2192
- Indexed
- SCIE
SCOPUS
KCI
- Journal Title
- BULLETIN OF THE KOREAN CHEMICAL SOCIETY
- Volume
- 33
- Number
- 7
- Start Page
- 2187
- End Page
- 2192
- URI
- https://scholarworks.bwise.kr/hanyang/handle/2021.sw.hanyang/165201
- DOI
- 10.5012/bkcs.2012.33.7.2187
- ISSN
- 0253-2964
- Abstract
- This study presents a facile way synthesizing disc-like lipid bilyaer nanostructures with a cationic amphiphilic polyelectrolyte. The cationic amphiphilic polyelectrolyte was in a form of partially quarternized copolymer and was synthesized with 2-(dimethylamino)ethyl methacrylate and stearyl methacrylate. At some concentration ranges of the polymer, the addition of the polymer to lipid components during the preparation of bilayer nanostructures resulted in discs with a fairly high yield (similar to 99%). The mechanism for the formation of the nanostructures was discussed based on the physical properties of these nanostructures and by comparing the nanostructures obtained with an anionic amphiphilic polyelectrolyte.
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